Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA1931 PH-797804 0.6
uM
 3
MMP-3
 415.0 28
N2586 JNK-IN-8 3.0
uM
 3
MMP-3
 361.0 15
N2586 PH-797804 0.6
uM
 3
MMP-3
 175.0 15
0
MMP-3
 42.5 50
0
MMP-3
 37.5 34
0
MMP-3
 43.5 26
RA2159 5z-7-oxozeaenol 0.6
uM
 4
MMP-3
 82.5 66
RA2159 IKK16 2.0
uM
 4
MMP-3
 77.5 60
N2645 5z-7-oxozeaenol 0.6
uM
 4
MMP-3
 42.5 60
N2645 IKK16 2.0
uM
 4
MMP-3
 50.0 40
RA2708 5z-7-oxozeaenol 0.6
uM
 4
MMP-3
 370.0 67
RA2708 IKK16 2.0
uM
 4
MMP-3
 435.5 52
RA2159 Tofacitinib 0.3
uM
 4
MMP-3
 68.0 59
RA2159 4
MMP-3
 116.0 55
N2645 Tofacitinib 0.3
uM
 4
MMP-3
 43.0 42
N2645 4
MMP-3
 41.5 52
RA2708 Tofacitinib 0.3
uM
 4
MMP-3
 517.0 35
RA2708 4
MMP-3
 668.0 70
RA2159 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 4
MMP-3
 70.0 47
RA2159 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 4
MMP-3
 158.0 41
N2645 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 4
MMP-3
 39.0 73
N2645 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 4
MMP-3
 47.0 50
RA2708 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 4
MMP-3
 357.0 50
RA2708 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 4
MMP-3
 1235.0 57
RA2159 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 4
MMP-3
 108.5 54