Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA1931 Tofacitinib 0.3
uM
 1
MMP-3
 305.0 53
RA1931 1
MMP-3
 320.5 40
N2586 Tofacitinib 0.3
uM
 1
MMP-3
 379.0 19
N2586 1
MMP-3
 493.5 50
RA1869 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 1
MMP-3
 464.0 31
RA1869 IKK16 2.0
uM
 TNF-a 100
ng/mL
 1
MMP-3
 910.5 34
N2759 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 1
MMP-3
 238.0 23
N2759 IKK16 2.0
uM
 TNF-a 100
ng/mL
 1
MMP-3
 72.0 27
RA1931 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 1
MMP-3
 310.5 16
RA1931 IKK16 2.0
uM
 TNF-a 100
ng/mL
 1
MMP-3
 387.5 56
N2586 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 1
MMP-3
 291.0 32
N2586 IKK16 2.0
uM
 TNF-a 100
ng/mL
 1
MMP-3
 382.5 20
RA1869 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
MMP-3
 3262.0 39
RA1869 TNF-a 100
ng/mL
 1
MMP-3
 4571.0 27
N2759 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
MMP-3
 11540.0 25
N2759 TNF-a 100
ng/mL
 1
MMP-3
 12063.0 57
RA1931 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
MMP-3
 590.0 11
RA1931 TNF-a 100
ng/mL
 1
MMP-3
 893.0 44
N2586 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
MMP-3
 2779.0 21
N2586 TNF-a 100
ng/mL
 1
MMP-3
 2741.0 11
RA1869 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
MMP-3
 387.0 19
RA1869 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
MMP-3
 1791.5 42
N2759 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
MMP-3
 314.0 34
N2759 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
MMP-3
 937.0 28
RA1931 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
MMP-3
 227.5 74