Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2586 PH-797804 0.6
uM
 Poly(I:C) 2
ug/mL
 3
MMP-2
 338.5 20
RA1869 IL-1 alpha 100
ng/mL
 3
MMP-2
 943.0 33
N2759 IL-1 alpha 100
ng/mL
 3
MMP-2
 244.5 26
RA1931 IL-1 alpha 100
ng/mL
 3
MMP-2
 582.5 14
N2586 IL-1 alpha 100
ng/mL
 3
MMP-2
 544.0 32
RA1869 JNK-IN-8 3.0
uM
 IL-1 alpha 100
ng/mL
 3
MMP-2
 533.0 30
RA1869 PH-797804 0.6
uM
 IL-1 alpha 100
ng/mL
 3
MMP-2
 574.5 30
N2759 JNK-IN-8 3.0
uM
 IL-1 alpha 100
ng/mL
 3
MMP-2
 350.0 47
N2759 PH-797804 0.6
uM
 IL-1 alpha 100
ng/mL
 3
MMP-2
 265.0 15
RA1931 JNK-IN-8 3.0
uM
 IL-1 alpha 100
ng/mL
 3
MMP-2
 769.0 20
RA1931 PH-797804 0.6
uM
 IL-1 alpha 100
ng/mL
 3
MMP-2
 420.0 22
N2586 JNK-IN-8 3.0
uM
 IL-1 alpha 100
ng/mL
 3
MMP-2
 572.0 21
N2586 PH-797804 0.6
uM
 IL-1 alpha 100
ng/mL
 3
MMP-2
 512.0 25
RA1869 TNF-a 100
ng/mL
 3
MMP-2
 618.0 19
N2759 TNF-a 100
ng/mL
 3
MMP-2
 245.0 21
RA1931 TNF-a 100
ng/mL
 3
MMP-2
 337.0 18
N2586 TNF-a 100
ng/mL
 3
MMP-2
 523.0 21
RA1869 JNK-IN-8 3.0
uM
 TNF-a 100
ng/mL
 3
MMP-2
 483.0 25
RA1869 PH-797804 0.6
uM
 TNF-a 100
ng/mL
 3
MMP-2
 367.5 14
N2759 JNK-IN-8 3.0
uM
 TNF-a 100
ng/mL
 3
MMP-2
 221.0 16
N2759 PH-797804 0.6
uM
 TNF-a 100
ng/mL
 3
MMP-2
 324.0 39
RA1931 JNK-IN-8 3.0
uM
 TNF-a 100
ng/mL
 3
MMP-2
 352.0 7
RA1931 PH-797804 0.6
uM
 TNF-a 100
ng/mL
 3
MMP-2
 413.0 24
N2586 JNK-IN-8 3.0
uM
 TNF-a 100
ng/mL
 3
MMP-2
 501.0 17
N2586 PH-797804 0.6
uM
 TNF-a 100
ng/mL
 3
MMP-2
 302.0 11