Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)
- Detail
- Small Molecules Studied
- Primary Cells Studied
- Proteins Studied
- Unclassified Perturbagens Studied
- Data Columns
- Results
Download: Excel (XLSX), Comma-separated (CSV)
Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Protein Stimulus | Other Stimulus | Stimulus Concentration | Stimulus Conc Unit | ExpPlate | Measured Protein | Measured Protein MFI (a.u.) | Bead Count |
---|---|---|---|---|---|---|---|---|---|---|---|
RA2159 | PH-797804 | 0.6 | uM | IL-1 alpha | 100 | ng/mL | 4 | MMP-2 | 181.0 | 26 | |
N2645 | JNK-IN-8 | 3.0 | uM | IL-1 alpha | 100 | ng/mL | 4 | MMP-2 | 80.5 | 18 | |
N2645 | PH-797804 | 0.6 | uM | IL-1 alpha | 100 | ng/mL | 4 | MMP-2 | 46.0 | 45 | |
RA2708 | JNK-IN-8 | 3.0 | uM | IL-1 alpha | 100 | ng/mL | 4 | MMP-2 | 602.0 | 47 | |
RA2708 | PH-797804 | 0.6 | uM | IL-1 alpha | 100 | ng/mL | 4 | MMP-2 | 525.0 | 49 | |
RA2159 | TNF-a | 100 | ng/mL | 4 | MMP-2 | 325.0 | 37 | ||||
N2645 | TNF-a | 100 | ng/mL | 4 | MMP-2 | 56.0 | 16 | ||||
RA2708 | TNF-a | 100 | ng/mL | 4 | MMP-2 | 422.5 | 22 | ||||
RA2159 | JNK-IN-8 | 3.0 | uM | TNF-a | 100 | ng/mL | 4 | MMP-2 | 554.0 | 33 | |
RA2159 | PH-797804 | 0.6 | uM | TNF-a | 100 | ng/mL | 4 | MMP-2 | 301.0 | 31 | |
N2645 | JNK-IN-8 | 3.0 | uM | TNF-a | 100 | ng/mL | 4 | MMP-2 | 56.0 | 26 | |
N2645 | PH-797804 | 0.6 | uM | TNF-a | 100 | ng/mL | 4 | MMP-2 | 86.0 | 37 | |
RA2708 | JNK-IN-8 | 3.0 | uM | TNF-a | 100 | ng/mL | 4 | MMP-2 | 389.5 | 24 | |
RA2708 | PH-797804 | 0.6 | uM | TNF-a | 100 | ng/mL | 4 | MMP-2 | 549.5 | 28 | |
0 | MMP-2 | 9.0 | 37 | ||||||||
0 | MMP-2 | 4.0 | 59 | ||||||||
0 | MMP-2 | 10.0 | 47 | ||||||||
RA2159 | 4 | MMP-2 | 156.0 | 35 | |||||||
N2645 | 4 | MMP-2 | 55.0 | 28 | |||||||
RA2708 | 4 | MMP-2 | 385.0 | 31 | |||||||
RA2159 | JNK-IN-8 | 3.0 | uM | 4 | MMP-2 | 272.0 | 43 | ||||
RA2159 | PH-797804 | 0.6 | uM | 4 | MMP-2 | 250.5 | 34 | ||||
N2645 | JNK-IN-8 | 3.0 | uM | 4 | MMP-2 | 61.0 | 46 | ||||
N2645 | PH-797804 | 0.6 | uM | 4 | MMP-2 | 57.0 | 30 | ||||
RA2708 | JNK-IN-8 | 3.0 | uM | 4 | MMP-2 | 482.0 | 36 |