Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)
- Detail
- Small Molecules Studied
- Primary Cells Studied
- Proteins Studied
- Unclassified Perturbagens Studied
- Data Columns
- Results
Download: Excel (XLSX), Comma-separated (CSV)
Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Protein Stimulus | Other Stimulus | Stimulus Concentration | Stimulus Conc Unit | ExpPlate | Measured Protein | Measured Protein MFI (a.u.) | Bead Count |
---|---|---|---|---|---|---|---|---|---|---|---|
N2645 | JNK-IN-8 | 3.0 | uM | TNF-a | 100 | ng/mL | 2 | MMP-2 | 83.0 | 45 | |
N2645 | PH-797804 | 0.6 | uM | TNF-a | 100 | ng/mL | 2 | MMP-2 | 81.0 | 48 | |
RA2708 | JNK-IN-8 | 3.0 | uM | TNF-a | 100 | ng/mL | 2 | MMP-2 | 513.0 | 32 | |
RA2708 | PH-797804 | 0.6 | uM | TNF-a | 100 | ng/mL | 2 | MMP-2 | 434.5 | 40 | |
RA2159 | IL-1 alpha | 100 | ng/mL | 2 | MMP-2 | 315.0 | 22 | ||||
N2645 | IL-1 alpha | 100 | ng/mL | 2 | MMP-2 | 82.0 | 48 | ||||
RA2708 | IL-1 alpha | 100 | ng/mL | 2 | MMP-2 | 344.0 | 45 | ||||
RA2159 | JNK-IN-8 | 3.0 | uM | IL-1 alpha | 100 | ng/mL | 2 | MMP-2 | 621.0 | 31 | |
RA2159 | PH-797804 | 0.6 | uM | IL-1 alpha | 100 | ng/mL | 2 | MMP-2 | 341.0 | 35 | |
N2645 | JNK-IN-8 | 3.0 | uM | IL-1 alpha | 100 | ng/mL | 2 | MMP-2 | 85.0 | 35 | |
N2645 | PH-797804 | 0.6 | uM | IL-1 alpha | 100 | ng/mL | 2 | MMP-2 | 96.5 | 32 | |
RA2708 | JNK-IN-8 | 3.0 | uM | IL-1 alpha | 100 | ng/mL | 2 | MMP-2 | 789.0 | 22 | |
RA2708 | PH-797804 | 0.6 | uM | IL-1 alpha | 100 | ng/mL | 2 | MMP-2 | 499.0 | 35 | |
RA2159 | Poly(I:C) | 2 | ug/mL | 2 | MMP-2 | 208.5 | 50 | ||||
N2645 | Poly(I:C) | 2 | ug/mL | 2 | MMP-2 | 86.0 | 44 | ||||
RA2708 | Poly(I:C) | 2 | ug/mL | 2 | MMP-2 | 310.0 | 40 | ||||
RA2159 | JNK-IN-8 | 3.0 | uM | Poly(I:C) | 2 | ug/mL | 2 | MMP-2 | 320.5 | 38 | |
RA2159 | PH-797804 | 0.6 | uM | Poly(I:C) | 2 | ug/mL | 2 | MMP-2 | 287.0 | 46 | |
N2645 | JNK-IN-8 | 3.0 | uM | Poly(I:C) | 2 | ug/mL | 2 | MMP-2 | 70.0 | 36 | |
N2645 | PH-797804 | 0.6 | uM | Poly(I:C) | 2 | ug/mL | 2 | MMP-2 | 80.5 | 22 | |
RA2708 | JNK-IN-8 | 3.0 | uM | Poly(I:C) | 2 | ug/mL | 2 | MMP-2 | 472.0 | 37 | |
RA2708 | PH-797804 | 0.6 | uM | Poly(I:C) | 2 | ug/mL | 2 | MMP-2 | 439.0 | 37 | |
RA2159 | 2 | MMP-2 | 230.0 | 44 | |||||||
N2645 | 2 | MMP-2 | 88.0 | 45 | |||||||
RA2708 | 2 | MMP-2 | 318.0 | 43 |