Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA1869 5z-7-oxozeaenol 0.6
uM
 1
MMP-2
 392.0 32
RA1869 IKK16 2.0
uM
 1
MMP-2
 797.0 35
N2759 5z-7-oxozeaenol 0.6
uM
 1
MMP-2
 244.5 32
N2759 IKK16 2.0
uM
 1
MMP-2
 319.0 29
RA1931 5z-7-oxozeaenol 0.6
uM
 1
MMP-2
 466.0 27
RA1931 IKK16 2.0
uM
 1
MMP-2
 454.0 30
N2586 5z-7-oxozeaenol 0.6
uM
 1
MMP-2
 381.0 28
N2586 IKK16 2.0
uM
 1
MMP-2
 373.5 50
RA1869 Tofacitinib 0.3
uM
 1
MMP-2
 561.0 21
RA1869 1
MMP-2
 590.5 38
N2759 Tofacitinib 0.3
uM
 1
MMP-2
 286.0 49
N2759 1
MMP-2
 265.0 22
RA1931 Tofacitinib 0.3
uM
 1
MMP-2
 312.0 47
RA1931 1
MMP-2
 422.0 31
N2586 Tofacitinib 0.3
uM
 1
MMP-2
 427.5 26
N2586 1
MMP-2
 303.5 40
RA1869 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 1
MMP-2
 457.0 29
RA1869 IKK16 2.0
uM
 TNF-a 100
ng/mL
 1
MMP-2
 499.0 28
N2759 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 1
MMP-2
 114.5 16
N2759 IKK16 2.0
uM
 TNF-a 100
ng/mL
 1
MMP-2
 211.0 19
RA1931 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 1
MMP-2
 270.0 21
RA1931 IKK16 2.0
uM
 TNF-a 100
ng/mL
 1
MMP-2
 402.0 41
N2586 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 1
MMP-2
 213.0 31
N2586 IKK16 2.0
uM
 TNF-a 100
ng/mL
 1
MMP-2
 410.0 14
RA1869 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
MMP-2
 718.0 20