Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)
- Detail
- Small Molecules Studied
- Primary Cells Studied
- Proteins Studied
- Unclassified Perturbagens Studied
- Data Columns
- Results
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Protein Stimulus | Other Stimulus | Stimulus Concentration | Stimulus Conc Unit | ExpPlate | Measured Protein | Measured Protein MFI (a.u.) | Bead Count |
|---|---|---|---|---|---|---|---|---|---|---|---|
| TNF-a | 100 | ng/mL | 0 | MMP-1 | 16.0 | 67 | |||||
| IL-1 alpha | 100 | ng/mL | 0 | MMP-1 | 22.0 | 49 | |||||
| Poly(I:C) | 2 | ug/mL | 0 | MMP-1 | 21.5 | 34 | |||||
| TNF-a | 100 | ng/mL | 0 | MMP-1 | 17.5 | 38 | |||||
| IL-1 alpha | 100 | ng/mL | 0 | MMP-1 | 18.0 | 49 | |||||
| Poly(I:C) | 2 | ug/mL | 0 | MMP-1 | 14.5 | 54 | |||||
| TNF-a | 100 | ng/mL | 0 | MMP-1 | 39.0 | 47 | |||||
| IL-1 alpha | 100 | ng/mL | 0 | MMP-1 | 29.0 | 47 | |||||
| Poly(I:C) | 2 | ug/mL | 0 | MMP-1 | 24.0 | 40 | |||||
| TNF-a | 100 | ng/mL | 0 | MMP-1 | 22.0 | 35 | |||||
| IL-1 alpha | 100 | ng/mL | 0 | MMP-1 | 25.5 | 48 | |||||
| Poly(I:C) | 2 | ug/mL | 0 | MMP-1 | 21.5 | 42 | |||||
| 0 | MMP-2 | 4.0 | 50 | ||||||||
| 0 | MMP-2 | 10.0 | 35 | ||||||||
| 0 | MMP-2 | 4.5 | 18 | ||||||||
| RA1869 | 1 | MMP-2 | 1267.0 | 42 | |||||||
| N2759 | 1 | MMP-2 | 287.5 | 26 | |||||||
| RA1931 | 1 | MMP-2 | 374.0 | 24 | |||||||
| N2586 | 1 | MMP-2 | 480.0 | 39 | |||||||
| RA1869 | JNK-IN-8 | 3.0 | uM | 1 | MMP-2 | 718.0 | 33 | ||||
| RA1869 | PH-797804 | 0.6 | uM | 1 | MMP-2 | 690.5 | 34 | ||||
| N2759 | JNK-IN-8 | 3.0 | uM | 1 | MMP-2 | 304.0 | 35 | ||||
| N2759 | PH-797804 | 0.6 | uM | 1 | MMP-2 | 383.0 | 27 | ||||
| RA1931 | JNK-IN-8 | 3.0 | uM | 1 | MMP-2 | 536.0 | 33 | ||||
| RA1931 | PH-797804 | 0.6 | uM | 1 | MMP-2 | 435.5 | 28 |