Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2586 JNK-IN-8 3.0
uM
 3
MMP-1
 1310.5 28
N2586 PH-797804 0.6
uM
 3
MMP-1
 2253.5 24
0
MMP-1
 29.0 76
0
MMP-1
 26.0 40
0
MMP-1
 22.0 47
RA2159 5z-7-oxozeaenol 0.6
uM
 4
MMP-1
 210.0 68
RA2159 IKK16 2.0
uM
 4
MMP-1
 269.0 89
N2645 5z-7-oxozeaenol 0.6
uM
 4
MMP-1
 56.0 76
N2645 IKK16 2.0
uM
 4
MMP-1
 58.0 54
RA2708 5z-7-oxozeaenol 0.6
uM
 4
MMP-1
 719.0 57
RA2708 IKK16 2.0
uM
 4
MMP-1
 1304.0 49
RA2159 Tofacitinib 0.3
uM
 4
MMP-1
 236.5 64
RA2159 4
MMP-1
 198.0 87
N2645 Tofacitinib 0.3
uM
 4
MMP-1
 96.5 40
N2645 4
MMP-1
 74.0 69
RA2708 Tofacitinib 0.3
uM
 4
MMP-1
 987.0 55
RA2708 4
MMP-1
 920.0 59
RA2159 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 4
MMP-1
 197.0 86
RA2159 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 4
MMP-1
 454.0 47
N2645 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 4
MMP-1
 72.0 55
N2645 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 4
MMP-1
 61.0 72
RA2708 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 4
MMP-1
 568.0 74
RA2708 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 4
MMP-1
 2496.0 77
RA2159 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 4
MMP-1
 338.0 60
RA2159 Poly(I:C) 2
ug/mL
 4
MMP-1
 466.0 61