Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2759 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
CTACK
 30.0 65
N2759 IL-1 alpha 100
ng/mL
 3
CTACK
 31.5 66
RA1931 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
CTACK
 34.0 52
RA1931 IL-1 alpha 100
ng/mL
 3
CTACK
 36.0 48
N2586 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
CTACK
 26.5 52
N2586 IL-1 alpha 100
ng/mL
 3
CTACK
 31.0 41
RA1869 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
CTACK
 16.0 57
RA1869 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
CTACK
 17.0 66
N2759 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
CTACK
 14.0 65
N2759 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
CTACK
 17.0 76
RA1931 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
CTACK
 16.0 70
RA1931 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
CTACK
 13.0 79
N2586 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
CTACK
 15.0 57
N2586 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
CTACK
 21.0 58
RA1869 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 3
CTACK
 15.0 55
RA1869 TNF-a 100
ng/mL
 3
CTACK
 15.0 58
N2759 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 3
CTACK
 17.5 62
N2759 TNF-a 100
ng/mL
 3
CTACK
 20.0 67
RA1931 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 3
CTACK
 16.0 70
RA1931 TNF-a 100
ng/mL
 3
CTACK
 17.5 36
N2586 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 3
CTACK
 18.5 64
N2586 TNF-a 100
ng/mL
 3
CTACK
 18.0 62
RA1869 5z-7-oxozeaenol 0.6
uM
 3
CTACK
 14.0 57
RA1869 IKK16 2.0
uM
 3
CTACK
 14.0 63
N2759 5z-7-oxozeaenol 0.6
uM
 3
CTACK
 15.0 69