Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA1869 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 3
CTACK
 14.0 72
N2759 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 3
CTACK
 15.0 53
N2759 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 3
CTACK
 18.0 65
RA1931 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 3
CTACK
 15.0 67
RA1931 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 3
CTACK
 16.0 70
N2586 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 3
CTACK
 15.0 68
N2586 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 3
CTACK
 17.0 61
RA1869 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 3
CTACK
 15.0 60
RA1869 Poly(I:C) 2
ug/mL
 3
CTACK
 15.5 52
N2759 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 3
CTACK
 16.0 63
N2759 Poly(I:C) 2
ug/mL
 3
CTACK
 18.0 59
RA1931 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 3
CTACK
 15.0 46
RA1931 Poly(I:C) 2
ug/mL
 3
CTACK
 17.0 67
N2586 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 3
CTACK
 16.0 71
N2586 Poly(I:C) 2
ug/mL
 3
CTACK
 16.0 53
RA1869 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
CTACK
 27.0 61
RA1869 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
CTACK
 25.0 50
N2759 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
CTACK
 32.0 77
N2759 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
CTACK
 30.0 76
RA1931 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
CTACK
 26.0 63
RA1931 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
CTACK
 30.0 61
N2586 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
CTACK
 29.0 73
N2586 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
CTACK
 29.0 68
RA1869 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
CTACK
 26.0 75
RA1869 IL-1 alpha 100
ng/mL
 3
CTACK
 27.0 60