Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2159 5z-7-oxozeaenol 0.6
uM
 4
IL-6
 3513.0 30
N2645 JNK-IN-8 3.0
uM
 4
MIP-1B
 44.5 30
N2759 JNK-IN-8 3.0
uM
 IL-1 alpha 100
ng/mL
 3
IL-16
 83.5 30
RA2159 PH-797804 0.6
uM
 IL-1 alpha 100
ng/mL
 4
PDGF-BB
 51.5 30
RA2159 JNK-IN-8 3.0
uM
 Poly(I:C) 2
ug/mL
 4
PDGF-BB
 28.5 30
N2645 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 4
IL-1B
 17.5 30
RA1869 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
IL-16
 18.0 30
RA1931 Tofacitinib 0.3
uM
 3
IL-2
 47.0 30
N2645 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 4
IL-12 (p70)
 36.0 30
RA2159 JNK-IN-8 3.0
uM
 IL-1 alpha 100
ng/mL
 4
IL-17
 85.5 30
RA1931 IKK16 2.0
uM
 1
MMP-2
 454.0 30
N2645 Poly(I:C) 2
ug/mL
 4
IL-10
 36.0 30
RA2708 PH-797804 0.6
uM
 4
PDGF-BB
 26.5 30
N2645 JNK-IN-8 3.0
uM
 IL-1 alpha 100
ng/mL
 4
IL-8
 9653.0 30
N2645 IKK16 2.0
uM
 4
MIP-1B
 67.0 30
RA2159 JNK-IN-8 3.0
uM
 Poly(I:C) 2
ug/mL
 4
RANTES
 22637.5 30
RA2708 PH-797804 0.6
uM
 4
FGF Basic
 43.5 30
RA2708 JNK-IN-8 3.0
uM
 4
RANTES
 26.5 30
0
MIG
 13.0 30
RA2708 PH-797804 0.6
uM
 IL-1 alpha 100
ng/mL
 4
RANTES
 9791.5 30
N2586 PH-797804 0.6
uM
 TNF-a 100
ng/mL
 3
IL3
 29.0 30
RA2159 JNK-IN-8 3.0
uM
 4
PDGF-BB
 21.5 30
RA2159 Tofacitinib 0.3
uM
 2
IL2-Ra
 38.5 30
RA1931 TNF-a 100
ng/mL
 3
IL-16
 56.5 30
RA2708 PH-797804 0.6
uM
 2
SCF
 38.5 30