Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2645 PH-797804 0.6
uM
 2
SCF
 27.5 48
RA2708 JNK-IN-8 3.0
uM
 2
SCF
 30.0 28
RA2708 PH-797804 0.6
uM
 2
SCF
 31.5 46
RA2159 5z-7-oxozeaenol 0.6
uM
 2
SCF
 40.0 64
RA2159 IKK16 2.0
uM
 2
SCF
 44.5 52
N2645 5z-7-oxozeaenol 0.6
uM
 2
SCF
 32.0 53
N2645 IKK16 2.0
uM
 2
SCF
 31.5 64
RA2708 5z-7-oxozeaenol 0.6
uM
 2
SCF
 29.0 46
RA2708 IKK16 2.0
uM
 2
SCF
 32.0 59
RA2159 Tofacitinib 0.3
uM
 2
SCF
 39.5 50
RA2159 2
SCF
 39.0 59
N2645 Tofacitinib 0.3
uM
 2
SCF
 30.0 61
N2645 2
SCF
 35.0 51
RA2708 Tofacitinib 0.3
uM
 2
SCF
 36.0 52
RA2708 2
SCF
 32.0 42
RA2159 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
SCF
 37.5 50
RA2159 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
SCF
 41.0 67
N2645 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
SCF
 32.5 58
N2645 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
SCF
 29.0 55
RA2708 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
SCF
 29.0 57
RA2708 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
SCF
 35.5 64
RA2159 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
SCF
 46.0 58
RA2159 TNF-a 100
ng/mL
 2
SCF
 46.0 56
N2645 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
SCF
 32.0 41
N2645 TNF-a 100
ng/mL
 2
SCF
 30.0 37