Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2708 JNK-IN-8 3.0
uM
 2
IL1-a
 374.0 39
RA2708 PH-797804 0.6
uM
 2
IL1-a
 209.0 37
RA2159 5z-7-oxozeaenol 0.6
uM
 2
IL1-a
 401.0 56
RA2159 IKK16 2.0
uM
 2
IL1-a
 231.0 57
N2645 5z-7-oxozeaenol 0.6
uM
 2
IL1-a
 281.0 49
N2645 IKK16 2.0
uM
 2
IL1-a
 341.0 57
RA2708 5z-7-oxozeaenol 0.6
uM
 2
IL1-a
 304.0 53
RA2708 IKK16 2.0
uM
 2
IL1-a
 313.0 55
RA2159 Tofacitinib 0.3
uM
 2
IL1-a
 280.0 59
RA2159 2
IL1-a
 258.5 68
N2645 Tofacitinib 0.3
uM
 2
IL1-a
 270.0 55
N2645 2
IL1-a
 244.0 57
RA2708 Tofacitinib 0.3
uM
 2
IL1-a
 413.5 44
RA2708 2
IL1-a
 335.0 38
RA2159 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
IL1-a
 274.0 61
RA2159 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
IL1-a
 230.0 64
N2645 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
IL1-a
 259.5 52
N2645 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
IL1-a
 251.0 53
RA2708 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
IL1-a
 328.5 52
RA2708 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
IL1-a
 305.0 47
RA2159 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
IL1-a
 273.5 44
RA2159 TNF-a 100
ng/mL
 2
IL1-a
 237.5 56
N2645 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
IL1-a
 220.0 53
N2645 TNF-a 100
ng/mL
 2
IL1-a
 234.0 55
RA2708 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
IL1-a
 470.0 40