Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2759 Tofacitinib 0.3
uM
 3
IL-16
 49.0 45
N2759 3
IL-16
 46.0 39
RA1931 Tofacitinib 0.3
uM
 3
IL-16
 19.0 46
RA1931 3
IL-16
 21.0 39
N2586 Tofacitinib 0.3
uM
 3
IL-16
 32.5 34
N2586 3
IL-16
 31.0 42
RA1869 3
IL-16
 16.0 35
N2759 3
IL-16
 55.5 46
RA1931 3
IL-16
 24.0 43
N2586 3
IL-16
 32.0 52
RA1869 JNK-IN-8 3.0
uM
 3
IL-16
 14.0 41
RA1869 PH-797804 0.6
uM
 3
IL-16
 17.0 38
N2759 JNK-IN-8 3.0
uM
 3
IL-16
 44.0 29
N2759 PH-797804 0.6
uM
 3
IL-16
 50.0 38
RA1931 JNK-IN-8 3.0
uM
 3
IL-16
 20.0 39
RA1931 PH-797804 0.6
uM
 3
IL-16
 21.0 41
N2586 JNK-IN-8 3.0
uM
 3
IL-16
 30.0 55
N2586 PH-797804 0.6
uM
 3
IL-16
 34.0 60
RA1869 Poly(I:C) 2
ug/mL
 3
IL-16
 13.0 21
N2759 Poly(I:C) 2
ug/mL
 3
IL-16
 69.0 41
RA1931 Poly(I:C) 2
ug/mL
 3
IL-16
 20.0 42
N2586 Poly(I:C) 2
ug/mL
 3
IL-16
 69.5 58
RA1869 JNK-IN-8 3.0
uM
 Poly(I:C) 2
ug/mL
 3
IL-16
 15.0 40
RA1869 PH-797804 0.6
uM
 Poly(I:C) 2
ug/mL
 3
IL-16
 15.5 50
N2759 JNK-IN-8 3.0
uM
 Poly(I:C) 2
ug/mL
 3
IL-16
 54.0 39