Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA1931 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
MCP3
 33.0 65
N2586 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
MCP3
 21.0 76
N2586 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
MCP3
 26.0 81
RA1869 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
MCP3
 213.0 61
RA1869 IL-1 alpha 100
ng/mL
 3
MCP3
 267.0 71
N2759 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
MCP3
 107.0 77
N2759 IL-1 alpha 100
ng/mL
 3
MCP3
 103.0 63
RA1931 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
MCP3
 266.5 70
RA1931 IL-1 alpha 100
ng/mL
 3
MCP3
 421.0 76
N2586 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
MCP3
 194.0 85
N2586 IL-1 alpha 100
ng/mL
 3
MCP3
 186.0 67
RA1869 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
MCP3
 16.0 61
RA1869 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
MCP3
 31.0 88
N2759 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
MCP3
 19.0 95
N2759 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
MCP3
 21.0 75
RA1931 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
MCP3
 17.0 81
RA1931 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
MCP3
 23.0 73
N2586 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
MCP3
 18.0 80
N2586 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
MCP3
 27.0 55
RA1869 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 3
MCP3
 33.0 78
RA1869 TNF-a 100
ng/mL
 3
MCP3
 43.5 64
N2759 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 3
MCP3
 23.0 72
N2759 TNF-a 100
ng/mL
 3
MCP3
 23.0 64
RA1931 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 3
MCP3
 28.0 69
RA1931 TNF-a 100
ng/mL
 3
MCP3
 32.5 48