Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA1931 Tofacitinib 0.3
uM
 3
MCP3
 18.0 65
RA1931 3
MCP3
 21.0 59
N2586 Tofacitinib 0.3
uM
 3
MCP3
 20.5 66
N2586 3
MCP3
 19.0 66
RA1869 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 3
MCP3
 19.5 66
RA1869 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 3
MCP3
 29.0 84
N2759 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 3
MCP3
 16.0 81
N2759 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 3
MCP3
 16.0 80
RA1931 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 3
MCP3
 18.0 68
RA1931 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 3
MCP3
 21.0 66
N2586 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 3
MCP3
 18.0 78
N2586 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 3
MCP3
 20.0 65
RA1869 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 3
MCP3
 28.0 67
RA1869 Poly(I:C) 2
ug/mL
 3
MCP3
 85.0 77
N2759 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 3
MCP3
 21.5 56
N2759 Poly(I:C) 2
ug/mL
 3
MCP3
 22.0 75
RA1931 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 3
MCP3
 35.0 66
RA1931 Poly(I:C) 2
ug/mL
 3
MCP3
 49.0 79
N2586 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 3
MCP3
 38.0 77
N2586 Poly(I:C) 2
ug/mL
 3
MCP3
 36.0 66
RA1869 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
MCP3
 22.0 64
RA1869 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
MCP3
 39.5 96
N2759 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
MCP3
 22.0 82
N2759 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
MCP3
 23.0 89
RA1931 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
MCP3
 23.5 88