Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2759 IKK16 2.0
uM
TNF-a 100
ng/mL
3
MIG
138.0 49
RA1931 5z-7-oxozeaenol 0.6
uM
TNF-a 100
ng/mL
3
MIG
26.0 54
RA1931 IKK16 2.0
uM
TNF-a 100
ng/mL
3
MIG
42.0 51
N2586 5z-7-oxozeaenol 0.6
uM
TNF-a 100
ng/mL
3
MIG
38.0 65
N2586 IKK16 2.0
uM
TNF-a 100
ng/mL
3
MIG
93.5 52
RA1869 Tofacitinib 0.3
uM
TNF-a 100
ng/mL
3
MIG
30.5 64
RA1869 TNF-a 100
ng/mL
3
MIG
38.0 63
N2759 Tofacitinib 0.3
uM
TNF-a 100
ng/mL
3
MIG
205.5 52
N2759 TNF-a 100
ng/mL
3
MIG
224.0 68
RA1931 Tofacitinib 0.3
uM
TNF-a 100
ng/mL
3
MIG
61.0 57
RA1931 TNF-a 100
ng/mL
3
MIG
67.0 37
N2586 Tofacitinib 0.3
uM
TNF-a 100
ng/mL
3
MIG
151.0 53
N2586 TNF-a 100
ng/mL
3
MIG
153.0 76
RA1869 5z-7-oxozeaenol 0.6
uM
3
MIG
13.5 54
RA1869 IKK16 2.0
uM
3
MIG
16.0 62
N2759 5z-7-oxozeaenol 0.6
uM
3
MIG
40.0 70
N2759 IKK16 2.0
uM
3
MIG
42.0 81
RA1931 5z-7-oxozeaenol 0.6
uM
3
MIG
15.0 68
RA1931 IKK16 2.0
uM
3
MIG
16.0 63
N2586 5z-7-oxozeaenol 0.6
uM
3
MIG
31.0 67
N2586 IKK16 2.0
uM
3
MIG
36.0 61
RA1869 Tofacitinib 0.3
uM
3
MIG
14.0 55
RA1869 3
MIG
13.0 49
N2759 Tofacitinib 0.3
uM
3
MIG
44.0 59
N2759 3
MIG
43.0 41