Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2759 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 3
MIG
 88.0 50
N2759 Poly(I:C) 2
ug/mL
 3
MIG
 72.0 45
RA1931 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 3
MIG
 22.0 53
RA1931 Poly(I:C) 2
ug/mL
 3
MIG
 24.5 58
N2586 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 3
MIG
 74.0 53
N2586 Poly(I:C) 2
ug/mL
 3
MIG
 63.0 33
RA1869 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
MIG
 25.0 71
RA1869 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
MIG
 25.0 65
N2759 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
MIG
 46.0 67
N2759 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
MIG
 64.0 75
RA1931 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
MIG
 28.0 59
RA1931 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
MIG
 33.0 53
N2586 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
MIG
 35.0 59
N2586 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
MIG
 49.0 73
RA1869 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
MIG
 32.0 63
RA1869 IL-1 alpha 100
ng/mL
 3
MIG
 27.0 55
N2759 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
MIG
 115.0 60
N2759 IL-1 alpha 100
ng/mL
 3
MIG
 97.0 51
RA1931 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
MIG
 47.0 41
RA1931 IL-1 alpha 100
ng/mL
 3
MIG
 51.0 56
N2586 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
MIG
 113.0 79
N2586 IL-1 alpha 100
ng/mL
 3
MIG
 87.5 46
RA1869 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
MIG
 19.0 54
RA1869 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
MIG
 27.0 58
N2759 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
MIG
 38.5 66