Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2586 IKK16 2.0
uM
 TNF-a 100
ng/mL
 1
MIG
 141.0 53
RA1869 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
MIG
 42.0 51
RA1869 TNF-a 100
ng/mL
 1
MIG
 56.0 59
N2759 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
MIG
 338.0 60
N2759 TNF-a 100
ng/mL
 1
MIG
 268.0 66
RA1931 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
MIG
 78.5 68
RA1931 TNF-a 100
ng/mL
 1
MIG
 87.5 56
N2586 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
MIG
 190.0 33
N2586 TNF-a 100
ng/mL
 1
MIG
 223.0 57
RA1869 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
MIG
 24.0 49
RA1869 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
MIG
 23.0 46
N2759 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
MIG
 62.0 69
N2759 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
MIG
 94.0 66
RA1931 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
MIG
 27.5 64
RA1931 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
MIG
 28.0 52
N2586 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
MIG
 53.5 60
N2586 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
MIG
 48.5 64
RA1869 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
MIG
 44.0 49
RA1869 IL-1 alpha 100
ng/mL
 1
MIG
 35.5 44
N2759 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
MIG
 138.5 68
N2759 IL-1 alpha 100
ng/mL
 1
MIG
 122.0 49
RA1931 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
MIG
 50.0 46
RA1931 IL-1 alpha 100
ng/mL
 1
MIG
 46.0 53
N2586 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
MIG
 141.0 39
N2586 IL-1 alpha 100
ng/mL
 1
MIG
 119.5 42