Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2708 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 4
IL-16
 38.5 56
RA2708 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 4
IL-16
 62.0 54
RA2159 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 4
IL-16
 51.0 51
RA2159 IL-1 alpha 100
ng/mL
 4
IL-16
 42.0 45
N2645 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 4
IL-16
 81.5 54
N2645 IL-1 alpha 100
ng/mL
 4
IL-16
 66.0 53
RA2708 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 4
IL-16
 93.0 55
RA2708 IL-1 alpha 100
ng/mL
 4
IL-16
 83.5 34
RA2159 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 4
IL-16
 33.0 48
RA2159 IKK16 2.0
uM
 TNF-a 100
ng/mL
 4
IL-16
 45.0 62
N2645 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 4
IL-16
 40.5 52
N2645 IKK16 2.0
uM
 TNF-a 100
ng/mL
 4
IL-16
 52.5 54
RA2708 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 4
IL-16
 41.0 61
RA2708 IKK16 2.0
uM
 TNF-a 100
ng/mL
 4
IL-16
 99.5 54
RA2159 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 4
IL-16
 73.0 54
RA2159 TNF-a 100
ng/mL
 4
IL-16
 70.0 63
N2645 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 4
IL-16
 65.5 58
N2645 TNF-a 100
ng/mL
 4
IL-16
 66.0 64
RA2708 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 4
IL-16
 223.0 43
RA2708 TNF-a 100
ng/mL
 4
IL-16
 192.5 50
RA2159 5z-7-oxozeaenol 0.6
uM
 4
IL-16
 33.0 41
RA2159 IKK16 2.0
uM
 4
IL-16
 23.0 43
N2645 5z-7-oxozeaenol 0.6
uM
 4
IL-16
 23.0 50
N2645 IKK16 2.0
uM
 4
IL-16
 22.5 46
RA2708 5z-7-oxozeaenol 0.6
uM
 4
IL-16
 30.5 56