Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
TNF-a 100
ng/mL
 0
IL-7
 11.0 47
IL-1 alpha 100
ng/mL
 0
IL-7
 10.5 54
Poly(I:C) 2
ug/mL
 0
IL-7
 10.0 56
TNF-a 100
ng/mL
 0
IL-7
 9.5 36
IL-1 alpha 100
ng/mL
 0
IL-7
 8.0 37
Poly(I:C) 2
ug/mL
 0
IL-7
 7.0 41
TNF-a 100
ng/mL
 0
IL-7
 11.0 19
IL-1 alpha 100
ng/mL
 0
IL-7
 7.5 16
Poly(I:C) 2
ug/mL
 0
IL-7
 10.0 16
TNF-a 100
ng/mL
 0
IL-7
 9.0 19
IL-1 alpha 100
ng/mL
 0
IL-7
 9.0 39
Poly(I:C) 2
ug/mL
 0
IL-7
 7.0 27
0
IL-12 (p70)
 21.0 57
0
IL-12 (p70)
 19.5 64
0
IL-12 (p70)
 22.0 45
RA1869 1
IL-12 (p70)
 106.5 42
N2759 1
IL-12 (p70)
 84.0 69
RA1931 1
IL-12 (p70)
 68.5 64
N2586 1
IL-12 (p70)
 71.5 56
RA1869 JNK-IN-8 3.0
uM
 1
IL-12 (p70)
 71.0 58
RA1869 PH-797804 0.6
uM
 1
IL-12 (p70)
 82.0 54
N2759 JNK-IN-8 3.0
uM
 1
IL-12 (p70)
 80.0 59
N2759 PH-797804 0.6
uM
 1
IL-12 (p70)
 80.5 66
RA1931 JNK-IN-8 3.0
uM
 1
IL-12 (p70)
 64.0 56
RA1931 PH-797804 0.6
uM
 1
IL-12 (p70)
 76.0 74