Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)
- Detail
- Small Molecules Studied
- Primary Cells Studied
- Proteins Studied
- Unclassified Perturbagens Studied
- Data Columns
- Results
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Protein Stimulus | Other Stimulus | Stimulus Concentration | Stimulus Conc Unit | ExpPlate | Measured Protein | Measured Protein MFI (a.u.) | Bead Count |
|---|---|---|---|---|---|---|---|---|---|---|---|
| N2645 | PH-797804 | 0.6 | uM | IL-1 alpha | 100 | ng/mL | 4 | IL-10 | 37.5 | 24 | |
| RA2708 | JNK-IN-8 | 3.0 | uM | IL-1 alpha | 100 | ng/mL | 4 | IL-10 | 42.0 | 26 | |
| RA2708 | PH-797804 | 0.6 | uM | IL-1 alpha | 100 | ng/mL | 4 | IL-10 | 60.0 | 23 | |
| RA2159 | TNF-a | 100 | ng/mL | 4 | IL-10 | 61.5 | 34 | ||||
| N2645 | TNF-a | 100 | ng/mL | 4 | IL-10 | 48.0 | 33 | ||||
| RA2708 | TNF-a | 100 | ng/mL | 4 | IL-10 | 46.0 | 22 | ||||
| RA2159 | JNK-IN-8 | 3.0 | uM | TNF-a | 100 | ng/mL | 4 | IL-10 | 55.5 | 20 | |
| RA2159 | PH-797804 | 0.6 | uM | TNF-a | 100 | ng/mL | 4 | IL-10 | 55.0 | 28 | |
| N2645 | JNK-IN-8 | 3.0 | uM | TNF-a | 100 | ng/mL | 4 | IL-10 | 41.0 | 27 | |
| N2645 | PH-797804 | 0.6 | uM | TNF-a | 100 | ng/mL | 4 | IL-10 | 43.0 | 34 | |
| RA2708 | JNK-IN-8 | 3.0 | uM | TNF-a | 100 | ng/mL | 4 | IL-10 | 54.0 | 29 | |
| RA2708 | PH-797804 | 0.6 | uM | TNF-a | 100 | ng/mL | 4 | IL-10 | 41.0 | 28 | |
| 0 | IL-10 | 25.0 | 24 | ||||||||
| 0 | IL-10 | 29.0 | 37 | ||||||||
| 0 | IL-10 | 28.0 | 27 | ||||||||
| RA2159 | 4 | IL-10 | 40.5 | 30 | |||||||
| N2645 | 4 | IL-10 | 40.5 | 28 | |||||||
| RA2708 | 4 | IL-10 | 41.0 | 26 | |||||||
| RA2159 | JNK-IN-8 | 3.0 | uM | 4 | IL-10 | 34.0 | 15 | ||||
| RA2159 | PH-797804 | 0.6 | uM | 4 | IL-10 | 39.0 | 15 | ||||
| N2645 | JNK-IN-8 | 3.0 | uM | 4 | IL-10 | 27.0 | 25 | ||||
| N2645 | PH-797804 | 0.6 | uM | 4 | IL-10 | 29.0 | 21 | ||||
| RA2708 | JNK-IN-8 | 3.0 | uM | 4 | IL-10 | 39.0 | 22 | ||||
| RA2708 | PH-797804 | 0.6 | uM | 4 | IL-10 | 43.0 | 36 | ||||
| TNF-a | 100 | ng/mL | 0 | IL-10 | 55.0 | 61 |