Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2586 Poly(I:C) 2
ug/mL
3
IL-8
8356.0 54
RA1869 5z-7-oxozeaenol 0.6
uM
IL-1 alpha 100
ng/mL
3
IL-8
88.0 49
RA1869 IKK16 2.0
uM
IL-1 alpha 100
ng/mL
3
IL-8
2702.0 63
N2759 5z-7-oxozeaenol 0.6
uM
IL-1 alpha 100
ng/mL
3
IL-8
200.0 53
N2759 IKK16 2.0
uM
IL-1 alpha 100
ng/mL
3
IL-8
3695.0 78
RA1931 5z-7-oxozeaenol 0.6
uM
IL-1 alpha 100
ng/mL
3
IL-8
146.0 65
RA1931 IKK16 2.0
uM
IL-1 alpha 100
ng/mL
3
IL-8
3553.0 62
N2586 5z-7-oxozeaenol 0.6
uM
IL-1 alpha 100
ng/mL
3
IL-8
177.0 71
N2586 IKK16 2.0
uM
IL-1 alpha 100
ng/mL
3
IL-8
1945.5 62
RA1869 Tofacitinib 0.3
uM
IL-1 alpha 100
ng/mL
3
IL-8
11162.0 61
RA1869 IL-1 alpha 100
ng/mL
3
IL-8
12485.5 58
N2759 Tofacitinib 0.3
uM
IL-1 alpha 100
ng/mL
3
IL-8
11576.0 59
N2759 IL-1 alpha 100
ng/mL
3
IL-8
12318.0 64
RA1931 Tofacitinib 0.3
uM
IL-1 alpha 100
ng/mL
3
IL-8
11943.0 67
RA1931 IL-1 alpha 100
ng/mL
3
IL-8
12843.0 62
N2586 Tofacitinib 0.3
uM
IL-1 alpha 100
ng/mL
3
IL-8
11534.0 57
N2586 IL-1 alpha 100
ng/mL
3
IL-8
11577.0 63
RA1869 5z-7-oxozeaenol 0.6
uM
TNF-a 100
ng/mL
3
IL-8
301.0 39
RA1869 IKK16 2.0
uM
TNF-a 100
ng/mL
3
IL-8
4734.0 55
N2759 5z-7-oxozeaenol 0.6
uM
TNF-a 100
ng/mL
3
IL-8
220.5 54
N2759 IKK16 2.0
uM
TNF-a 100
ng/mL
3
IL-8
4885.0 74
RA1931 5z-7-oxozeaenol 0.6
uM
TNF-a 100
ng/mL
3
IL-8
732.0 61
RA1931 IKK16 2.0
uM
TNF-a 100
ng/mL
3
IL-8
2677.0 57
N2586 5z-7-oxozeaenol 0.6
uM
TNF-a 100
ng/mL
3
IL-8
418.0 65
N2586 IKK16 2.0
uM
TNF-a 100
ng/mL
3
IL-8
5482.0 59