Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)
- Detail
- Small Molecules Studied
- Primary Cells Studied
- Proteins Studied
- Unclassified Perturbagens Studied
- Data Columns
- Results
Download: Excel (XLSX), Comma-separated (CSV)
Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Protein Stimulus | Other Stimulus | Stimulus Concentration | Stimulus Conc Unit | ExpPlate | Measured Protein | Measured Protein MFI (a.u.) | Bead Count |
---|---|---|---|---|---|---|---|---|---|---|---|
N2586 | Poly(I:C) | 2 | ug/mL | 3 | IL-8 | 8356.0 | 54 | ||||
RA1869 | 5z-7-oxozeaenol | 0.6 | uM | IL-1 alpha | 100 | ng/mL | 3 | IL-8 | 88.0 | 49 | |
RA1869 | IKK16 | 2.0 | uM | IL-1 alpha | 100 | ng/mL | 3 | IL-8 | 2702.0 | 63 | |
N2759 | 5z-7-oxozeaenol | 0.6 | uM | IL-1 alpha | 100 | ng/mL | 3 | IL-8 | 200.0 | 53 | |
N2759 | IKK16 | 2.0 | uM | IL-1 alpha | 100 | ng/mL | 3 | IL-8 | 3695.0 | 78 | |
RA1931 | 5z-7-oxozeaenol | 0.6 | uM | IL-1 alpha | 100 | ng/mL | 3 | IL-8 | 146.0 | 65 | |
RA1931 | IKK16 | 2.0 | uM | IL-1 alpha | 100 | ng/mL | 3 | IL-8 | 3553.0 | 62 | |
N2586 | 5z-7-oxozeaenol | 0.6 | uM | IL-1 alpha | 100 | ng/mL | 3 | IL-8 | 177.0 | 71 | |
N2586 | IKK16 | 2.0 | uM | IL-1 alpha | 100 | ng/mL | 3 | IL-8 | 1945.5 | 62 | |
RA1869 | Tofacitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 3 | IL-8 | 11162.0 | 61 | |
RA1869 | IL-1 alpha | 100 | ng/mL | 3 | IL-8 | 12485.5 | 58 | ||||
N2759 | Tofacitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 3 | IL-8 | 11576.0 | 59 | |
N2759 | IL-1 alpha | 100 | ng/mL | 3 | IL-8 | 12318.0 | 64 | ||||
RA1931 | Tofacitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 3 | IL-8 | 11943.0 | 67 | |
RA1931 | IL-1 alpha | 100 | ng/mL | 3 | IL-8 | 12843.0 | 62 | ||||
N2586 | Tofacitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 3 | IL-8 | 11534.0 | 57 | |
N2586 | IL-1 alpha | 100 | ng/mL | 3 | IL-8 | 11577.0 | 63 | ||||
RA1869 | 5z-7-oxozeaenol | 0.6 | uM | TNF-a | 100 | ng/mL | 3 | IL-8 | 301.0 | 39 | |
RA1869 | IKK16 | 2.0 | uM | TNF-a | 100 | ng/mL | 3 | IL-8 | 4734.0 | 55 | |
N2759 | 5z-7-oxozeaenol | 0.6 | uM | TNF-a | 100 | ng/mL | 3 | IL-8 | 220.5 | 54 | |
N2759 | IKK16 | 2.0 | uM | TNF-a | 100 | ng/mL | 3 | IL-8 | 4885.0 | 74 | |
RA1931 | 5z-7-oxozeaenol | 0.6 | uM | TNF-a | 100 | ng/mL | 3 | IL-8 | 732.0 | 61 | |
RA1931 | IKK16 | 2.0 | uM | TNF-a | 100 | ng/mL | 3 | IL-8 | 2677.0 | 57 | |
N2586 | 5z-7-oxozeaenol | 0.6 | uM | TNF-a | 100 | ng/mL | 3 | IL-8 | 418.0 | 65 | |
N2586 | IKK16 | 2.0 | uM | TNF-a | 100 | ng/mL | 3 | IL-8 | 5482.0 | 59 |