Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2645 PH-797804 0.6
uM
 2
IL-8
 82.0 55
RA2708 JNK-IN-8 3.0
uM
 2
IL-8
 272.5 44
RA2708 PH-797804 0.6
uM
 2
IL-8
 288.0 59
RA2159 5z-7-oxozeaenol 0.6
uM
 2
IL-8
 57.5 62
RA2159 IKK16 2.0
uM
 2
IL-8
 79.0 73
N2645 5z-7-oxozeaenol 0.6
uM
 2
IL-8
 59.0 60
N2645 IKK16 2.0
uM
 2
IL-8
 79.0 68
RA2708 5z-7-oxozeaenol 0.6
uM
 2
IL-8
 224.0 65
RA2708 IKK16 2.0
uM
 2
IL-8
 282.0 79
RA2159 Tofacitinib 0.3
uM
 2
IL-8
 68.0 67
RA2159 2
IL-8
 90.0 65
N2645 Tofacitinib 0.3
uM
 2
IL-8
 122.0 93
N2645 2
IL-8
 110.0 68
RA2708 Tofacitinib 0.3
uM
 2
IL-8
 328.5 66
RA2708 2
IL-8
 419.0 62
RA2159 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
IL-8
 232.5 60
RA2159 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
IL-8
 5605.0 36
N2645 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
IL-8
 713.0 54
N2645 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
IL-8
 858.5 60
RA2708 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
IL-8
 422.0 57
RA2708 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
IL-8
 6108.0 56
RA2159 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
IL-8
 10825.0 67
RA2159 TNF-a 100
ng/mL
 2
IL-8
 10601.0 46
N2645 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
IL-8
 8896.0 63
N2645 TNF-a 100
ng/mL
 2
IL-8
 9320.0 54