Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2159 JNK-IN-8 3.0
uM
 2
MMP-2
 333.0 35
RA2159 PH-797804 0.6
uM
 2
MMP-2
 231.5 50
N2645 JNK-IN-8 3.0
uM
 2
MMP-2
 68.0 37
N2645 PH-797804 0.6
uM
 2
MMP-2
 70.0 21
RA2708 JNK-IN-8 3.0
uM
 2
MMP-2
 492.0 34
RA2708 PH-797804 0.6
uM
 2
MMP-2
 295.0 47
RA2159 5z-7-oxozeaenol 0.6
uM
 2
MMP-2
 208.5 50
RA2159 IKK16 2.0
uM
 2
MMP-2
 365.5 50
N2645 5z-7-oxozeaenol 0.6
uM
 2
MMP-2
 65.0 47
N2645 IKK16 2.0
uM
 2
MMP-2
 88.0 44
RA2708 5z-7-oxozeaenol 0.6
uM
 2
MMP-2
 327.0 47
RA2708 IKK16 2.0
uM
 2
MMP-2
 328.0 31
RA2159 Tofacitinib 0.3
uM
 2
MMP-2
 173.0 41
RA2159 2
MMP-2
 220.0 39
N2645 Tofacitinib 0.3
uM
 2
MMP-2
 71.5 56
N2645 2
MMP-2
 91.0 44
RA2708 Tofacitinib 0.3
uM
 2
MMP-2
 289.5 34
RA2708 2
MMP-2
 257.0 35
RA2159 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
MMP-2
 114.0 34
RA2159 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
MMP-2
 284.0 50
N2645 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
MMP-2
 55.0 41
N2645 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
MMP-2
 63.0 51
RA2708 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
MMP-2
 191.0 36
RA2708 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
MMP-2
 298.0 33
RA2159 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
MMP-2
 331.0 39