Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2586 PH-797804 0.6
uM
TNF-a 100
ng/mL
1
MMP-1
11244.0 37
RA1869 IL-1 alpha 100
ng/mL
1
MMP-1
31651.5 60
N2759 IL-1 alpha 100
ng/mL
1
MMP-1
24839.5 46
RA1931 IL-1 alpha 100
ng/mL
1
MMP-1
10998.0 41
N2586 IL-1 alpha 100
ng/mL
1
MMP-1
20173.0 29
RA1869 JNK-IN-8 3.0
uM
IL-1 alpha 100
ng/mL
1
MMP-1
31537.5 46
RA1869 PH-797804 0.6
uM
IL-1 alpha 100
ng/mL
1
MMP-1
15631.0 35
N2759 JNK-IN-8 3.0
uM
IL-1 alpha 100
ng/mL
1
MMP-1
35462.0 19
N2759 PH-797804 0.6
uM
IL-1 alpha 100
ng/mL
1
MMP-1
12847.0 23
RA1931 JNK-IN-8 3.0
uM
IL-1 alpha 100
ng/mL
1
MMP-1
17457.0 31
RA1931 PH-797804 0.6
uM
IL-1 alpha 100
ng/mL
1
MMP-1
10148.0 31
N2586 JNK-IN-8 3.0
uM
IL-1 alpha 100
ng/mL
1
MMP-1
28525.0 21
N2586 PH-797804 0.6
uM
IL-1 alpha 100
ng/mL
1
MMP-1
12494.5 26
RA1869 Poly(I:C) 2
ug/mL
1
MMP-1
3852.0 35
N2759 Poly(I:C) 2
ug/mL
1
MMP-1
3149.0 40
RA1931 Poly(I:C) 2
ug/mL
1
MMP-1
5613.5 42
N2586 Poly(I:C) 2
ug/mL
1
MMP-1
2978.0 39
RA1869 JNK-IN-8 3.0
uM
Poly(I:C) 2
ug/mL
1
MMP-1
4682.5 36
RA1869 PH-797804 0.6
uM
Poly(I:C) 2
ug/mL
1
MMP-1
5099.0 23
N2759 JNK-IN-8 3.0
uM
Poly(I:C) 2
ug/mL
1
MMP-1
1872.0 29
N2759 PH-797804 0.6
uM
Poly(I:C) 2
ug/mL
1
MMP-1
2703.0 35
RA1931 JNK-IN-8 3.0
uM
Poly(I:C) 2
ug/mL
1
MMP-1
6936.5 24
RA1931 PH-797804 0.6
uM
Poly(I:C) 2
ug/mL
1
MMP-1
6940.5 32
N2586 JNK-IN-8 3.0
uM
Poly(I:C) 2
ug/mL
1
MMP-1
5479.0 34
N2586 PH-797804 0.6
uM
Poly(I:C) 2
ug/mL
1
MMP-1
1933.0 32