Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2586 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 1
IL-1RA
 31.5 44
N2586 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 1
IL-1RA
 25.0 38
0
IL-1RA
 23.0 39
RA2159 2
IL-1RA
 24.0 65
RA2159 EO1428 1.0
uM
 2
IL-1RA
 26.0 75
RA2159 PI103 0.1
uM
 2
IL-1RA
 27.0 62
RA2159 Sigma A6730 3.0
uM
 2
IL-1RA
 24.0 54
RA2159 JNK-IN-8 3.0
uM
 2
IL-1RA
 26.0 46
RA2159 JNK-IN-11 0.3
uM
 2
IL-1RA
 22.5 60
RA2159 2
IL-1RA
 23.0 44
N2586 2
IL-1RA
 26.0 45
N2586 EO1428 1.0
uM
 2
IL-1RA
 26.0 47
N2586 PI103 0.1
uM
 2
IL-1RA
 28.0 51
N2586 Sigma A6730 3.0
uM
 2
IL-1RA
 25.5 36
N2586 JNK-IN-8 3.0
uM
 2
IL-1RA
 24.0 59
N2586 JNK-IN-11 0.3
uM
 2
IL-1RA
 25.0 53
N2586 2
IL-1RA
 25.0 35
0
IL-1RA
 20.0 52
0
IL-1RA
 24.0 50
RA2159 TNF-a 100
ng/mL
 2
IL-1RA
 45.0 67
RA2159 EO1428 1.0
uM
 TNF-a 100
ng/mL
 2
IL-1RA
 46.5 58
RA2159 PI103 0.1
uM
 TNF-a 100
ng/mL
 2
IL-1RA
 44.0 56
RA2159 Sigma A6730 3.0
uM
 TNF-a 100
ng/mL
 2
IL-1RA
 40.0 61
RA2159 JNK-IN-8 3.0
uM
 TNF-a 100
ng/mL
 2
IL-1RA
 33.0 59
RA2159 JNK-IN-11 0.3
uM
 TNF-a 100
ng/mL
 2
IL-1RA
 35.0 51