Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2586 JNK-IN-8 3.0
uM
 3
IL-16
 20.0 67
RA2159 IL-17A 100
ng/mL
 3
IL-16
 17.0 55
RA2159 PD184352 0.1
uM
 IL-17A 100
ng/mL
 3
IL-16
 17.0 57
RA2159 Lestaurtinib 0.3
uM
 IL-17A 100
ng/mL
 3
IL-16
 19.0 79
RA2159 Ruxolitinib 0.3
uM
 IL-17A 100
ng/mL
 3
IL-16
 16.0 74
RA2159 Tofacitinib 0.3
uM
 IL-17A 100
ng/mL
 3
IL-16
 19.0 75
RA2159 IKK16 2.0
uM
 IL-17A 100
ng/mL
 3
IL-16
 19.0 66
N2586 IL-17A 100
ng/mL
 3
IL-16
 18.0 83
N2586 PD184352 0.1
uM
 IL-17A 100
ng/mL
 3
IL-16
 15.0 59
N2586 Lestaurtinib 0.3
uM
 IL-17A 100
ng/mL
 3
IL-16
 18.0 69
N2586 Ruxolitinib 0.3
uM
 IL-17A 100
ng/mL
 3
IL-16
 23.0 71
N2586 Tofacitinib 0.3
uM
 IL-17A 100
ng/mL
 3
IL-16
 17.0 59
N2586 IKK16 2.0
uM
 IL-17A 100
ng/mL
 3
IL-16
 21.0 61
RA2159 IL-6 100
ug/mL
 3
IL-16
 16.0 55
RA2159 PD184352 0.1
uM
 IL-6 100
ug/mL
 3
IL-16
 16.5 58
RA2159 Lestaurtinib 0.3
uM
 IL-6 100
ug/mL
 3
IL-16
 15.0 69
RA2159 Ruxolitinib 0.3
uM
 IL-6 100
ug/mL
 3
IL-16
 13.0 56
RA2159 Tofacitinib 0.3
uM
 IL-6 100
ug/mL
 3
IL-16
 16.0 82
RA2159 IKK16 2.0
uM
 IL-6 100
ug/mL
 3
IL-16
 17.5 52
RA2159 Sigma A6730 3.0
uM
 3
IL-16
 15.5 50
N2586 IL-6 100
ug/mL
 3
IL-16
 21.0 68
N2586 PD184352 0.1
uM
 IL-6 100
ug/mL
 3
IL-16
 16.0 44
N2586 Lestaurtinib 0.3
uM
 IL-6 100
ug/mL
 3
IL-16
 18.0 63
N2586 Ruxolitinib 0.3
uM
 IL-6 100
ug/mL
 3
IL-16
 18.5 52
N2586 Tofacitinib 0.3
uM
 IL-6 100
ug/mL
 3
IL-16
 15.0 59