Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2159 TNF-a 100
ng/mL
 3
MCP3
 111.5 50
RA2159 PD184352 0.1
uM
 TNF-a 100
ng/mL
 3
MCP3
 86.0 50
RA2159 Lestaurtinib 0.3
uM
 TNF-a 100
ng/mL
 3
MCP3
 89.0 72
RA2159 Ruxolitinib 0.3
uM
 TNF-a 100
ng/mL
 3
MCP3
 97.0 39
RA2159 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 3
MCP3
 97.0 57
RA2159 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
MCP3
 42.0 53
RA2159 EO1428 1.0
uM
 3
MCP3
 21.0 43
N2586 TNF-a 100
ng/mL
 3
MCP3
 255.0 67
N2586 PD184352 0.1
uM
 TNF-a 100
ng/mL
 3
MCP3
 191.5 90
N2586 Lestaurtinib 0.3
uM
 TNF-a 100
ng/mL
 3
MCP3
 208.0 71
N2586 Ruxolitinib 0.3
uM
 TNF-a 100
ng/mL
 3
MCP3
 243.0 62
N2586 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 3
MCP3
 83.0 64
N2586 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
MCP3
 188.5 76
N2586 EO1428 1.0
uM
 3
MCP3
 60.0 65
0
MCP3
 14.0 51
RA2159 3
MCP3
 24.5 78
RA2159 PD184352 0.1
uM
 3
MCP3
 26.0 47
RA2159 Lestaurtinib 0.3
uM
 3
MCP3
 26.5 46
RA2159 Ruxolitinib 0.3
uM
 3
MCP3
 24.5 56
RA2159 Tofacitinib 0.3
uM
 3
MCP3
 22.0 63
RA2159 IKK16 2.0
uM
 3
MCP3
 22.0 41
RA2159 3
MCP3
 27.0 69
N2586 3
MCP3
 67.0 43
N2586 PD184352 0.1
uM
 3
MCP3
 47.0 45
N2586 Lestaurtinib 0.3
uM
 3
MCP3
 44.0 49