Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2159 IKK16 2.0
uM
 3
MCP3
 25.0 67
RA2159 JNK-IN-8 3.0
uM
 3
MCP3
 22.5 72
N2586 3
MCP3
 75.5 68
N2586 PD184352 0.1
uM
 3
MCP3
 77.0 89
N2586 Lestaurtinib 0.3
uM
 3
MCP3
 57.0 69
N2586 Ruxolitinib 0.3
uM
 3
MCP3
 92.0 63
N2586 Tofacitinib 0.3
uM
 3
MCP3
 56.0 73
N2586 IKK16 2.0
uM
 3
MCP3
 40.0 52
N2586 JNK-IN-8 3.0
uM
 3
MCP3
 56.0 63
RA2159 IL-17A 100
ng/mL
 3
MCP3
 24.0 66
RA2159 PD184352 0.1
uM
 IL-17A 100
ng/mL
 3
MCP3
 25.0 85
RA2159 Lestaurtinib 0.3
uM
 IL-17A 100
ng/mL
 3
MCP3
 26.5 70
RA2159 Ruxolitinib 0.3
uM
 IL-17A 100
ng/mL
 3
MCP3
 28.0 59
RA2159 Tofacitinib 0.3
uM
 IL-17A 100
ng/mL
 3
MCP3
 22.5 76
RA2159 IKK16 2.0
uM
 IL-17A 100
ng/mL
 3
MCP3
 22.0 57
N2586 IL-17A 100
ng/mL
 3
MCP3
 74.5 72
N2586 PD184352 0.1
uM
 IL-17A 100
ng/mL
 3
MCP3
 76.0 68
N2586 Lestaurtinib 0.3
uM
 IL-17A 100
ng/mL
 3
MCP3
 59.0 82
N2586 Ruxolitinib 0.3
uM
 IL-17A 100
ng/mL
 3
MCP3
 105.0 64
N2586 Tofacitinib 0.3
uM
 IL-17A 100
ng/mL
 3
MCP3
 50.5 56
N2586 IKK16 2.0
uM
 IL-17A 100
ng/mL
 3
MCP3
 48.0 56
RA2159 IL-6 100
ug/mL
 3
MCP3
 23.5 66
RA2159 PD184352 0.1
uM
 IL-6 100
ug/mL
 3
MCP3
 26.5 66
RA2159 Lestaurtinib 0.3
uM
 IL-6 100
ug/mL
 3
MCP3
 19.5 52
RA2159 Ruxolitinib 0.3
uM
 IL-6 100
ug/mL
 3
MCP3
 22.0 56