Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2159 IL-17A 100
ng/mL
 3
IFN-a2
 21.0 54
RA2159 PD184352 0.1
uM
 IL-17A 100
ng/mL
 3
IFN-a2
 20.0 52
RA2159 Lestaurtinib 0.3
uM
 IL-17A 100
ng/mL
 3
IFN-a2
 23.0 50
RA2159 Ruxolitinib 0.3
uM
 IL-17A 100
ng/mL
 3
IFN-a2
 24.0 50
RA2159 Tofacitinib 0.3
uM
 IL-17A 100
ng/mL
 3
IFN-a2
 20.0 77
RA2159 IKK16 2.0
uM
 IL-17A 100
ng/mL
 3
IFN-a2
 22.0 48
N2586 IL-17A 100
ng/mL
 3
IFN-a2
 58.0 76
N2586 PD184352 0.1
uM
 IL-17A 100
ng/mL
 3
IFN-a2
 59.0 54
N2586 Lestaurtinib 0.3
uM
 IL-17A 100
ng/mL
 3
IFN-a2
 44.0 73
N2586 Ruxolitinib 0.3
uM
 IL-17A 100
ng/mL
 3
IFN-a2
 100.0 61
N2586 Tofacitinib 0.3
uM
 IL-17A 100
ng/mL
 3
IFN-a2
 43.0 61
N2586 IKK16 2.0
uM
 IL-17A 100
ng/mL
 3
IFN-a2
 39.5 44
RA2159 IL-6 100
ug/mL
 3
IFN-a2
 21.0 53
RA2159 PD184352 0.1
uM
 IL-6 100
ug/mL
 3
IFN-a2
 20.0 69
RA2159 Lestaurtinib 0.3
uM
 IL-6 100
ug/mL
 3
IFN-a2
 21.5 44
RA2159 Ruxolitinib 0.3
uM
 IL-6 100
ug/mL
 3
IFN-a2
 16.0 65
RA2159 Tofacitinib 0.3
uM
 IL-6 100
ug/mL
 3
IFN-a2
 18.5 64
RA2159 IKK16 2.0
uM
 IL-6 100
ug/mL
 3
IFN-a2
 21.0 56
RA2159 Sigma A6730 3.0
uM
 3
IFN-a2
 21.5 72
N2586 IL-6 100
ug/mL
 3
IFN-a2
 52.0 57
N2586 PD184352 0.1
uM
 IL-6 100
ug/mL
 3
IFN-a2
 46.0 59
N2586 Lestaurtinib 0.3
uM
 IL-6 100
ug/mL
 3
IFN-a2
 37.0 58
N2586 Ruxolitinib 0.3
uM
 IL-6 100
ug/mL
 3
IFN-a2
 47.5 60
N2586 Tofacitinib 0.3
uM
 IL-6 100
ug/mL
 3
IFN-a2
 35.0 56
N2586 IKK16 2.0
uM
 IL-6 100
ug/mL
 3
IFN-a2
 38.0 69