Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
Poly(I:C) 2
ug/mL
 0
IL-16
 17.0 63
TNF-a 100
ng/mL
 0
IL-16
 17.0 39
IL-1 alpha 100
ng/mL
 0
IL-16
 21.0 80
IL-6 100
ug/mL
 0
IL-16
 21.0 78
IL-17A 100
ng/mL
 0
IL-16
 17.0 67
EGF 100
ng/mL
 0
IL-16
 17.0 64
IGF-I 100
ug/mL
 0
IL-16
 17.5 46
Adiponectin 5
ng/mL
 0
IL-16
 105.0 42
Leptin 1
ng/mL
 0
IL-16
 20.0 39
Visfatin 1
ng/mL
 0
IL-16
 17.0 64
Poly(I:C) 2
ug/mL
 0
IL-16
 20.0 38
0
IL12(p40)
 61.0 72
RA2159 1
IL12(p40)
 66.0 66
RA2159 PD184352 0.1
uM
 1
IL12(p40)
 63.0 61
RA2159 Lestaurtinib 0.3
uM
 1
IL12(p40)
 62.5 78
RA2159 Ruxolitinib 0.3
uM
 1
IL12(p40)
 60.0 58
RA2159 Tofacitinib 0.3
uM
 1
IL12(p40)
 72.0 56
RA2159 IKK16 2.0
uM
 1
IL12(p40)
 67.0 54
RA2159 1
IL12(p40)
 74.5 62
N2586 1
IL12(p40)
 70.5 68
N2586 PD184352 0.1
uM
 1
IL12(p40)
 62.0 63
N2586 Lestaurtinib 0.3
uM
 1
IL12(p40)
 76.0 63
N2586 Ruxolitinib 0.3
uM
 1
IL12(p40)
 71.5 58
N2586 Tofacitinib 0.3
uM
 1
IL12(p40)
 63.5 38
N2586 IKK16 2.0
uM
 1
IL12(p40)
 59.0 49