Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2586 JNK-IN-8 3.0
uM
 IL-6 100
ug/mL
 2
IFN-a2
 35.0 49
N2586 JNK-IN-11 0.3
uM
 IL-6 100
ug/mL
 2
IFN-a2
 33.0 60
N2586 Ruxolitinib 0.3
uM
 2
IFN-a2
 38.5 60
RA2159 IL-17A 100
ng/mL
 2
IFN-a2
 22.5 60
RA2159 EO1428 1.0
uM
 IL-17A 100
ng/mL
 2
IFN-a2
 21.0 55
RA2159 PI103 0.1
uM
 IL-17A 100
ng/mL
 2
IFN-a2
 23.0 67
RA2159 Sigma A6730 3.0
uM
 IL-17A 100
ng/mL
 2
IFN-a2
 26.5 78
RA2159 JNK-IN-8 3.0
uM
 IL-17A 100
ng/mL
 2
IFN-a2
 22.0 52
RA2159 JNK-IN-11 0.3
uM
 IL-17A 100
ng/mL
 2
IFN-a2
 22.0 43
RA2159 Tofacitinib 0.3
uM
 2
IFN-a2
 15.0 39
N2586 IL-17A 100
ng/mL
 2
IFN-a2
 49.0 55
N2586 EO1428 1.0
uM
 IL-17A 100
ng/mL
 2
IFN-a2
 61.0 79
N2586 PI103 0.1
uM
 IL-17A 100
ng/mL
 2
IFN-a2
 45.0 17
N2586 Sigma A6730 3.0
uM
 IL-17A 100
ng/mL
 2
IFN-a2
 62.0 16
N2586 JNK-IN-8 3.0
uM
 IL-17A 100
ng/mL
 2
IFN-a2
 37.5 52
N2586 JNK-IN-11 0.3
uM
 IL-17A 100
ng/mL
 2
IFN-a2
 40.0 55
N2586 Tofacitinib 0.3
uM
 2
IFN-a2
 33.0 72
RA2159 2
IFN-a2
 24.0 72
RA2159 EO1428 1.0
uM
 2
IFN-a2
 22.0 55
RA2159 PI103 0.1
uM
 2
IFN-a2
 20.0 44
RA2159 Sigma A6730 3.0
uM
 2
IFN-a2
 21.0 54
RA2159 JNK-IN-8 3.0
uM
 2
IFN-a2
 19.0 51
RA2159 JNK-IN-11 0.3
uM
 2
IFN-a2
 22.0 64
RA2159 IKK16 2.0
uM
 2
IFN-a2
 25.0 59
N2586 2
IFN-a2
 43.0 64