Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2159 JNK-IN-8 3.0
uM
 3
MIG
 20.0 66
N2586 3
MIG
 54.5 70
N2586 PD184352 0.1
uM
 3
MIG
 57.0 65
N2586 Lestaurtinib 0.3
uM
 3
MIG
 44.0 56
N2586 Ruxolitinib 0.3
uM
 3
MIG
 87.0 67
N2586 Tofacitinib 0.3
uM
 3
MIG
 45.0 62
N2586 IKK16 2.0
uM
 3
MIG
 34.0 71
N2586 JNK-IN-8 3.0
uM
 3
MIG
 41.0 54
RA2159 IL-17A 100
ng/mL
 3
MIG
 18.0 69
RA2159 PD184352 0.1
uM
 IL-17A 100
ng/mL
 3
MIG
 17.0 83
RA2159 Lestaurtinib 0.3
uM
 IL-17A 100
ng/mL
 3
MIG
 19.5 72
RA2159 Ruxolitinib 0.3
uM
 IL-17A 100
ng/mL
 3
MIG
 17.0 53
RA2159 Tofacitinib 0.3
uM
 IL-17A 100
ng/mL
 3
MIG
 19.0 69
RA2159 IKK16 2.0
uM
 IL-17A 100
ng/mL
 3
MIG
 20.5 52
N2586 IL-17A 100
ng/mL
 3
MIG
 57.0 51
N2586 PD184352 0.1
uM
 IL-17A 100
ng/mL
 3
MIG
 60.0 55
N2586 Lestaurtinib 0.3
uM
 IL-17A 100
ng/mL
 3
MIG
 43.0 50
N2586 Ruxolitinib 0.3
uM
 IL-17A 100
ng/mL
 3
MIG
 94.0 55
N2586 Tofacitinib 0.3
uM
 IL-17A 100
ng/mL
 3
MIG
 35.0 66
N2586 IKK16 2.0
uM
 IL-17A 100
ng/mL
 3
MIG
 34.0 49
RA2159 IL-6 100
ug/mL
 3
MIG
 15.0 59
RA2159 PD184352 0.1
uM
 IL-6 100
ug/mL
 3
MIG
 19.0 63
RA2159 Lestaurtinib 0.3
uM
 IL-6 100
ug/mL
 3
MIG
 16.0 61
RA2159 Ruxolitinib 0.3
uM
 IL-6 100
ug/mL
 3
MIG
 18.0 53
RA2159 Tofacitinib 0.3
uM
 IL-6 100
ug/mL
 3
MIG
 17.0 62