Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2586 JNK-IN-8 3.0
uM
Poly(I:C) 2
ug/mL
2
IL-17
40.0 39
N2586 JNK-IN-11 0.3
uM
Poly(I:C) 2
ug/mL
2
IL-17
55.0 46
0
IL-17
49.0 51
RA2159 Poly(I:C) 2
ug/mL
3
IL-17
65.5 78
RA2159 PD184352 0.1
uM
Poly(I:C) 2
ug/mL
3
IL-17
60.0 67
RA2159 Lestaurtinib 0.3
uM
Poly(I:C) 2
ug/mL
3
IL-17
52.0 61
RA2159 Ruxolitinib 0.3
uM
Poly(I:C) 2
ug/mL
3
IL-17
65.0 62
RA2159 Tofacitinib 0.3
uM
Poly(I:C) 2
ug/mL
3
IL-17
55.0 61
RA2159 IKK16 2.0
uM
Poly(I:C) 2
ug/mL
3
IL-17
56.0 69
N2586 Poly(I:C) 2
ug/mL
3
IL-17
65.5 78
N2586 PD184352 0.1
uM
Poly(I:C) 2
ug/mL
3
IL-17
58.0 57
N2586 Lestaurtinib 0.3
uM
Poly(I:C) 2
ug/mL
3
IL-17
68.0 61
N2586 Ruxolitinib 0.3
uM
Poly(I:C) 2
ug/mL
3
IL-17
68.0 74
N2586 Tofacitinib 0.3
uM
Poly(I:C) 2
ug/mL
3
IL-17
49.0 63
N2586 IKK16 2.0
uM
Poly(I:C) 2
ug/mL
3
IL-17
62.0 62
RA2159 3
IL-17
41.0 63
RA2159 PD184352 0.1
uM
3
IL-17
51.5 70
RA2159 Lestaurtinib 0.3
uM
3
IL-17
46.0 62
RA2159 Ruxolitinib 0.3
uM
3
IL-17
52.0 84
RA2159 Tofacitinib 0.3
uM
3
IL-17
51.0 68
RA2159 IKK16 2.0
uM
3
IL-17
52.0 66
RA2159 3
IL-17
53.0 72
N2586 3
IL-17
55.0 77
N2586 PD184352 0.1
uM
3
IL-17
55.0 90
N2586 Lestaurtinib 0.3
uM
3
IL-17
45.0 59