Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)
- Detail
- Small Molecules Studied
- Primary Cells Studied
- Proteins Studied
- Unclassified Perturbagens Studied
- Data Columns
- Results
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Protein Stimulus | Other Stimulus | Stimulus Concentration | Stimulus Conc Unit | ExpPlate | Measured Protein | Measured Protein MFI (a.u.) | Bead Count |
|---|---|---|---|---|---|---|---|---|---|---|---|
| N2586 | Lestaurtinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 3 | IL-12 (p70) | 98.0 | 55 | |
| N2586 | Ruxolitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 3 | IL-12 (p70) | 97.5 | 72 | |
| N2586 | Tofacitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 3 | IL-12 (p70) | 73.0 | 41 | |
| N2586 | IKK16 | 2.0 | uM | IL-1 alpha | 100 | ng/mL | 3 | IL-12 (p70) | 103.0 | 77 | |
| N2586 | PI103 | 0.1 | uM | 3 | IL-12 (p70) | 71.0 | 85 | ||||
| 0 | IL-12 (p70) | 14.0 | 53 | ||||||||
| RA2159 | TNF-a | 100 | ng/mL | 3 | IL-12 (p70) | 86.0 | 55 | ||||
| RA2159 | PD184352 | 0.1 | uM | TNF-a | 100 | ng/mL | 3 | IL-12 (p70) | 68.5 | 62 | |
| RA2159 | Lestaurtinib | 0.3 | uM | TNF-a | 100 | ng/mL | 3 | IL-12 (p70) | 52.0 | 67 | |
| RA2159 | Ruxolitinib | 0.3 | uM | TNF-a | 100 | ng/mL | 3 | IL-12 (p70) | 76.0 | 78 | |
| RA2159 | Tofacitinib | 0.3 | uM | TNF-a | 100 | ng/mL | 3 | IL-12 (p70) | 62.0 | 63 | |
| RA2159 | IKK16 | 2.0 | uM | TNF-a | 100 | ng/mL | 3 | IL-12 (p70) | 48.5 | 64 | |
| RA2159 | EO1428 | 1.0 | uM | 3 | IL-12 (p70) | 44.0 | 62 | ||||
| N2586 | TNF-a | 100 | ng/mL | 3 | IL-12 (p70) | 80.0 | 72 | ||||
| N2586 | PD184352 | 0.1 | uM | TNF-a | 100 | ng/mL | 3 | IL-12 (p70) | 73.0 | 68 | |
| N2586 | Lestaurtinib | 0.3 | uM | TNF-a | 100 | ng/mL | 3 | IL-12 (p70) | 74.5 | 78 | |
| N2586 | Ruxolitinib | 0.3 | uM | TNF-a | 100 | ng/mL | 3 | IL-12 (p70) | 43.0 | 49 | |
| N2586 | Tofacitinib | 0.3 | uM | TNF-a | 100 | ng/mL | 3 | IL-12 (p70) | 98.0 | 46 | |
| N2586 | IKK16 | 2.0 | uM | TNF-a | 100 | ng/mL | 3 | IL-12 (p70) | 92.5 | 70 | |
| N2586 | EO1428 | 1.0 | uM | 3 | IL-12 (p70) | 93.5 | 70 | ||||
| 0 | IL-12 (p70) | 9.0 | 66 | ||||||||
| RA2159 | 3 | IL-12 (p70) | 47.0 | 68 | |||||||
| RA2159 | PD184352 | 0.1 | uM | 3 | IL-12 (p70) | 58.0 | 55 | ||||
| RA2159 | Lestaurtinib | 0.3 | uM | 3 | IL-12 (p70) | 51.0 | 62 | ||||
| RA2159 | Ruxolitinib | 0.3 | uM | 3 | IL-12 (p70) | 66.5 | 52 |