Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)
- Detail
- Small Molecules Studied
- Primary Cells Studied
- Proteins Studied
- Unclassified Perturbagens Studied
- Data Columns
- Results
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Protein Stimulus | Other Stimulus | Stimulus Concentration | Stimulus Conc Unit | ExpPlate | Measured Protein | Measured Protein MFI (a.u.) | Bead Count |
|---|---|---|---|---|---|---|---|---|---|---|---|
| N2586 | Tofacitinib | 0.3 | uM | IL-17A | 100 | ng/mL | 3 | IL-12 (p70) | 108.0 | 51 | |
| N2586 | IKK16 | 2.0 | uM | IL-17A | 100 | ng/mL | 3 | IL-12 (p70) | 78.0 | 65 | |
| RA2159 | IL-6 | 100 | ug/mL | 3 | IL-12 (p70) | 57.0 | 78 | ||||
| RA2159 | PD184352 | 0.1 | uM | IL-6 | 100 | ug/mL | 3 | IL-12 (p70) | 52.0 | 75 | |
| RA2159 | Lestaurtinib | 0.3 | uM | IL-6 | 100 | ug/mL | 3 | IL-12 (p70) | 53.0 | 65 | |
| RA2159 | Ruxolitinib | 0.3 | uM | IL-6 | 100 | ug/mL | 3 | IL-12 (p70) | 40.5 | 74 | |
| RA2159 | Tofacitinib | 0.3 | uM | IL-6 | 100 | ug/mL | 3 | IL-12 (p70) | 47.0 | 77 | |
| RA2159 | IKK16 | 2.0 | uM | IL-6 | 100 | ug/mL | 3 | IL-12 (p70) | 36.0 | 59 | |
| RA2159 | Sigma A6730 | 3.0 | uM | 3 | IL-12 (p70) | 44.5 | 72 | ||||
| N2586 | IL-6 | 100 | ug/mL | 3 | IL-12 (p70) | 76.0 | 81 | ||||
| N2586 | PD184352 | 0.1 | uM | IL-6 | 100 | ug/mL | 3 | IL-12 (p70) | 67.0 | 63 | |
| N2586 | Lestaurtinib | 0.3 | uM | IL-6 | 100 | ug/mL | 3 | IL-12 (p70) | 51.0 | 69 | |
| N2586 | Ruxolitinib | 0.3 | uM | IL-6 | 100 | ug/mL | 3 | IL-12 (p70) | 78.0 | 79 | |
| N2586 | Tofacitinib | 0.3 | uM | IL-6 | 100 | ug/mL | 3 | IL-12 (p70) | 78.5 | 72 | |
| N2586 | IKK16 | 2.0 | uM | IL-6 | 100 | ug/mL | 3 | IL-12 (p70) | 83.0 | 57 | |
| N2586 | Sigma A6730 | 3.0 | uM | 3 | IL-12 (p70) | 70.5 | 70 | ||||
| RA2159 | IL-1 alpha | 100 | ng/mL | 3 | IL-12 (p70) | 89.0 | 61 | ||||
| RA2159 | PD184352 | 0.1 | uM | IL-1 alpha | 100 | ng/mL | 3 | IL-12 (p70) | 89.0 | 59 | |
| RA2159 | Lestaurtinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 3 | IL-12 (p70) | 67.5 | 52 | |
| RA2159 | Ruxolitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 3 | IL-12 (p70) | 84.5 | 60 | |
| RA2159 | Tofacitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 3 | IL-12 (p70) | 70.0 | 87 | |
| RA2159 | IKK16 | 2.0 | uM | IL-1 alpha | 100 | ng/mL | 3 | IL-12 (p70) | 45.0 | 52 | |
| RA2159 | PI103 | 0.1 | uM | 3 | IL-12 (p70) | 40.0 | 62 | ||||
| N2586 | IL-1 alpha | 100 | ng/mL | 3 | IL-12 (p70) | 102.0 | 66 | ||||
| N2586 | PD184352 | 0.1 | uM | IL-1 alpha | 100 | ng/mL | 3 | IL-12 (p70) | 68.0 | 77 |