Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2159 IL-17A 100
ng/mL
1
IL-7
17.0 84
RA2159 PD184352 0.1
uM
IL-17A 100
ng/mL
1
IL-7
10.5 72
RA2159 Lestaurtinib 0.3
uM
IL-17A 100
ng/mL
1
IL-7
13.0 79
RA2159 Ruxolitinib 0.3
uM
IL-17A 100
ng/mL
1
IL-7
15.0 80
RA2159 Tofacitinib 0.3
uM
IL-17A 100
ng/mL
1
IL-7
15.0 58
RA2159 IKK16 2.0
uM
IL-17A 100
ng/mL
1
IL-7
14.5 86
N2586 IL-17A 100
ng/mL
1
IL-7
20.0 87
N2586 PD184352 0.1
uM
IL-17A 100
ng/mL
1
IL-7
16.0 69
N2586 Lestaurtinib 0.3
uM
IL-17A 100
ng/mL
1
IL-7
23.5 70
N2586 Ruxolitinib 0.3
uM
IL-17A 100
ng/mL
1
IL-7
13.0 91
N2586 Tofacitinib 0.3
uM
IL-17A 100
ng/mL
1
IL-7
17.0 55
N2586 IKK16 2.0
uM
IL-17A 100
ng/mL
1
IL-7
17.0 77
RA2159 1
IL-7
17.0 68
RA2159 PD184352 0.1
uM
1
IL-7
13.0 89
RA2159 Lestaurtinib 0.3
uM
1
IL-7
16.0 80
RA2159 Ruxolitinib 0.3
uM
1
IL-7
13.5 74
RA2159 Tofacitinib 0.3
uM
1
IL-7
16.5 68
RA2159 IKK16 2.0
uM
1
IL-7
13.0 65
RA2159 JNK-IN-8 3.0
uM
1
IL-7
14.0 65
N2586 1
IL-7
17.5 80
N2586 PD184352 0.1
uM
1
IL-7
14.0 57
N2586 Lestaurtinib 0.3
uM
1
IL-7
18.5 56
N2586 Ruxolitinib 0.3
uM
1
IL-7
18.0 59
N2586 Tofacitinib 0.3
uM
1
IL-7
18.0 59
N2586 IKK16 2.0
uM
1
IL-7
15.0 77