Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)
- Detail
- Small Molecules Studied
- Primary Cells Studied
- Proteins Studied
- Unclassified Perturbagens Studied
- Data Columns
- Results
Download: Excel (XLSX), Comma-separated (CSV)
Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Protein Stimulus | Other Stimulus | Stimulus Concentration | Stimulus Conc Unit | ExpPlate | Measured Protein | Measured Protein MFI (a.u.) | Bead Count |
---|---|---|---|---|---|---|---|---|---|---|---|
RA2159 | IL-17A | 100 | ng/mL | 1 | IL-7 | 17.0 | 84 | ||||
RA2159 | PD184352 | 0.1 | uM | IL-17A | 100 | ng/mL | 1 | IL-7 | 10.5 | 72 | |
RA2159 | Lestaurtinib | 0.3 | uM | IL-17A | 100 | ng/mL | 1 | IL-7 | 13.0 | 79 | |
RA2159 | Ruxolitinib | 0.3 | uM | IL-17A | 100 | ng/mL | 1 | IL-7 | 15.0 | 80 | |
RA2159 | Tofacitinib | 0.3 | uM | IL-17A | 100 | ng/mL | 1 | IL-7 | 15.0 | 58 | |
RA2159 | IKK16 | 2.0 | uM | IL-17A | 100 | ng/mL | 1 | IL-7 | 14.5 | 86 | |
N2586 | IL-17A | 100 | ng/mL | 1 | IL-7 | 20.0 | 87 | ||||
N2586 | PD184352 | 0.1 | uM | IL-17A | 100 | ng/mL | 1 | IL-7 | 16.0 | 69 | |
N2586 | Lestaurtinib | 0.3 | uM | IL-17A | 100 | ng/mL | 1 | IL-7 | 23.5 | 70 | |
N2586 | Ruxolitinib | 0.3 | uM | IL-17A | 100 | ng/mL | 1 | IL-7 | 13.0 | 91 | |
N2586 | Tofacitinib | 0.3 | uM | IL-17A | 100 | ng/mL | 1 | IL-7 | 17.0 | 55 | |
N2586 | IKK16 | 2.0 | uM | IL-17A | 100 | ng/mL | 1 | IL-7 | 17.0 | 77 | |
RA2159 | 1 | IL-7 | 17.0 | 68 | |||||||
RA2159 | PD184352 | 0.1 | uM | 1 | IL-7 | 13.0 | 89 | ||||
RA2159 | Lestaurtinib | 0.3 | uM | 1 | IL-7 | 16.0 | 80 | ||||
RA2159 | Ruxolitinib | 0.3 | uM | 1 | IL-7 | 13.5 | 74 | ||||
RA2159 | Tofacitinib | 0.3 | uM | 1 | IL-7 | 16.5 | 68 | ||||
RA2159 | IKK16 | 2.0 | uM | 1 | IL-7 | 13.0 | 65 | ||||
RA2159 | JNK-IN-8 | 3.0 | uM | 1 | IL-7 | 14.0 | 65 | ||||
N2586 | 1 | IL-7 | 17.5 | 80 | |||||||
N2586 | PD184352 | 0.1 | uM | 1 | IL-7 | 14.0 | 57 | ||||
N2586 | Lestaurtinib | 0.3 | uM | 1 | IL-7 | 18.5 | 56 | ||||
N2586 | Ruxolitinib | 0.3 | uM | 1 | IL-7 | 18.0 | 59 | ||||
N2586 | Tofacitinib | 0.3 | uM | 1 | IL-7 | 18.0 | 59 | ||||
N2586 | IKK16 | 2.0 | uM | 1 | IL-7 | 15.0 | 77 |