Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)
- Detail
- Small Molecules Studied
- Primary Cells Studied
- Proteins Studied
- Unclassified Perturbagens Studied
- Data Columns
- Results
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Protein Stimulus | Other Stimulus | Stimulus Concentration | Stimulus Conc Unit | ExpPlate | Measured Protein | Measured Protein MFI (a.u.) | Bead Count |
|---|---|---|---|---|---|---|---|---|---|---|---|
| RA2159 | PD184352 | 0.1 | uM | IL-17A | 100 | ng/mL | 1 | IL-10 | 54.5 | 50 | |
| RA2159 | Lestaurtinib | 0.3 | uM | IL-17A | 100 | ng/mL | 1 | IL-10 | 54.0 | 63 | |
| RA2159 | Ruxolitinib | 0.3 | uM | IL-17A | 100 | ng/mL | 1 | IL-10 | 62.0 | 53 | |
| RA2159 | Tofacitinib | 0.3 | uM | IL-17A | 100 | ng/mL | 1 | IL-10 | 50.0 | 56 | |
| RA2159 | IKK16 | 2.0 | uM | IL-17A | 100 | ng/mL | 1 | IL-10 | 60.0 | 57 | |
| N2586 | IL-17A | 100 | ng/mL | 1 | IL-10 | 88.0 | 57 | ||||
| N2586 | PD184352 | 0.1 | uM | IL-17A | 100 | ng/mL | 1 | IL-10 | 70.0 | 47 | |
| N2586 | Lestaurtinib | 0.3 | uM | IL-17A | 100 | ng/mL | 1 | IL-10 | 81.0 | 62 | |
| N2586 | Ruxolitinib | 0.3 | uM | IL-17A | 100 | ng/mL | 1 | IL-10 | 65.5 | 70 | |
| N2586 | Tofacitinib | 0.3 | uM | IL-17A | 100 | ng/mL | 1 | IL-10 | 73.0 | 53 | |
| N2586 | IKK16 | 2.0 | uM | IL-17A | 100 | ng/mL | 1 | IL-10 | 64.5 | 50 | |
| RA2159 | 1 | IL-10 | 70.0 | 65 | |||||||
| RA2159 | PD184352 | 0.1 | uM | 1 | IL-10 | 59.0 | 57 | ||||
| RA2159 | Lestaurtinib | 0.3 | uM | 1 | IL-10 | 61.0 | 65 | ||||
| RA2159 | Ruxolitinib | 0.3 | uM | 1 | IL-10 | 51.0 | 60 | ||||
| RA2159 | Tofacitinib | 0.3 | uM | 1 | IL-10 | 73.0 | 47 | ||||
| RA2159 | IKK16 | 2.0 | uM | 1 | IL-10 | 53.5 | 64 | ||||
| RA2159 | JNK-IN-8 | 3.0 | uM | 1 | IL-10 | 60.0 | 45 | ||||
| N2586 | 1 | IL-10 | 72.0 | 53 | |||||||
| N2586 | PD184352 | 0.1 | uM | 1 | IL-10 | 60.5 | 42 | ||||
| N2586 | Lestaurtinib | 0.3 | uM | 1 | IL-10 | 75.0 | 35 | ||||
| N2586 | Ruxolitinib | 0.3 | uM | 1 | IL-10 | 74.0 | 53 | ||||
| N2586 | Tofacitinib | 0.3 | uM | 1 | IL-10 | 80.0 | 43 | ||||
| N2586 | IKK16 | 2.0 | uM | 1 | IL-10 | 79.0 | 61 | ||||
| N2586 | JNK-IN-8 | 3.0 | uM | 1 | IL-10 | 60.0 | 54 |