Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)
- Detail
- Small Molecules Studied
- Primary Cells Studied
- Proteins Studied
- Unclassified Perturbagens Studied
- Data Columns
- Results
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Protein Stimulus | Other Stimulus | Stimulus Concentration | Stimulus Conc Unit | ExpPlate | Measured Protein | Measured Protein MFI (a.u.) | Bead Count |
|---|---|---|---|---|---|---|---|---|---|---|---|
| RA2159 | Lestaurtinib | 0.3 | uM | IL-17A | 100 | ng/mL | 1 | MCP-1 (MCAF) | 4720.5 | 54 | |
| RA2159 | Ruxolitinib | 0.3 | uM | IL-17A | 100 | ng/mL | 1 | MCP-1 (MCAF) | 4324.0 | 77 | |
| RA2159 | Tofacitinib | 0.3 | uM | IL-17A | 100 | ng/mL | 1 | MCP-1 (MCAF) | 5167.0 | 73 | |
| RA2159 | IKK16 | 2.0 | uM | IL-17A | 100 | ng/mL | 1 | MCP-1 (MCAF) | 1711.0 | 62 | |
| N2586 | IL-17A | 100 | ng/mL | 1 | MCP-1 (MCAF) | 10234.0 | 79 | ||||
| N2586 | PD184352 | 0.1 | uM | IL-17A | 100 | ng/mL | 1 | MCP-1 (MCAF) | 9542.0 | 68 | |
| N2586 | Lestaurtinib | 0.3 | uM | IL-17A | 100 | ng/mL | 1 | MCP-1 (MCAF) | 9873.0 | 66 | |
| N2586 | Ruxolitinib | 0.3 | uM | IL-17A | 100 | ng/mL | 1 | MCP-1 (MCAF) | 9647.0 | 88 | |
| N2586 | Tofacitinib | 0.3 | uM | IL-17A | 100 | ng/mL | 1 | MCP-1 (MCAF) | 9171.0 | 77 | |
| N2586 | IKK16 | 2.0 | uM | IL-17A | 100 | ng/mL | 1 | MCP-1 (MCAF) | 6729.5 | 94 | |
| RA2159 | 1 | MCP-1 (MCAF) | 3524.0 | 96 | |||||||
| RA2159 | PD184352 | 0.1 | uM | 1 | MCP-1 (MCAF) | 1971.5 | 80 | ||||
| RA2159 | Lestaurtinib | 0.3 | uM | 1 | MCP-1 (MCAF) | 2440.5 | 72 | ||||
| RA2159 | Ruxolitinib | 0.3 | uM | 1 | MCP-1 (MCAF) | 3160.0 | 63 | ||||
| RA2159 | Tofacitinib | 0.3 | uM | 1 | MCP-1 (MCAF) | 3741.0 | 64 | ||||
| RA2159 | IKK16 | 2.0 | uM | 1 | MCP-1 (MCAF) | 1648.5 | 74 | ||||
| RA2159 | JNK-IN-8 | 3.0 | uM | 1 | MCP-1 (MCAF) | 1443.0 | 60 | ||||
| N2586 | 1 | MCP-1 (MCAF) | 7521.0 | 70 | |||||||
| N2586 | PD184352 | 0.1 | uM | 1 | MCP-1 (MCAF) | 6707.0 | 70 | ||||
| N2586 | Lestaurtinib | 0.3 | uM | 1 | MCP-1 (MCAF) | 6832.0 | 59 | ||||
| N2586 | Ruxolitinib | 0.3 | uM | 1 | MCP-1 (MCAF) | 6926.0 | 49 | ||||
| N2586 | Tofacitinib | 0.3 | uM | 1 | MCP-1 (MCAF) | 8502.0 | 49 | ||||
| N2586 | IKK16 | 2.0 | uM | 1 | MCP-1 (MCAF) | 5890.0 | 79 | ||||
| N2586 | JNK-IN-8 | 3.0 | uM | 1 | MCP-1 (MCAF) | 1907.0 | 67 | ||||
| RA2159 | EGF | 100 | ng/mL | 1 | MCP-1 (MCAF) | 3844.0 | 71 |