Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2586 JNK-IN-11 0.3
uM
4
IL-4
16.5 50
N2586 IKK16 2.0
uM
4
IL-4
16.0 50
RA2159 IL-17A 100
ng/mL
4
IL-4
21.0 48
RA2159 EO1428 1.0
uM
IL-17A 100
ng/mL
4
IL-4
21.0 65
RA2159 PI103 0.1
uM
IL-17A 100
ng/mL
4
IL-4
23.5 40
RA2159 Sigma A6730 3.0
uM
IL-17A 100
ng/mL
4
IL-4
21.0 43
RA2159 JNK-IN-8 3.0
uM
IL-17A 100
ng/mL
4
IL-4
24.0 30
RA2159 JNK-IN-11 0.3
uM
IL-17A 100
ng/mL
4
IL-4
25.0 45
RA2159 Tofacitinib 0.3
uM
4
IL-4
20.0 44
N2586 IL-17A 100
ng/mL
4
IL-4
22.0 49
N2586 EO1428 1.0
uM
IL-17A 100
ng/mL
4
IL-4
21.0 49
N2586 PI103 0.1
uM
IL-17A 100
ng/mL
4
IL-4
20.5 48
N2586 Sigma A6730 3.0
uM
IL-17A 100
ng/mL
4
IL-4
19.5 42
N2586 JNK-IN-8 3.0
uM
IL-17A 100
ng/mL
4
IL-4
19.0 45
N2586 JNK-IN-11 0.3
uM
IL-17A 100
ng/mL
4
IL-4
16.5 60
N2586 Tofacitinib 0.3
uM
4
IL-4
14.0 59
RA2159 IL-6 100
ug/mL
4
IL-4
26.0 53
RA2159 EO1428 1.0
uM
IL-6 100
ug/mL
4
IL-4
23.0 43
RA2159 PI103 0.1
uM
IL-6 100
ug/mL
4
IL-4
19.0 44
RA2159 Sigma A6730 3.0
uM
IL-6 100
ug/mL
4
IL-4
23.0 41
RA2159 JNK-IN-8 3.0
uM
IL-6 100
ug/mL
4
IL-4
19.0 35
RA2159 JNK-IN-11 0.3
uM
IL-6 100
ug/mL
4
IL-4
20.5 58
RA2159 Ruxolitinib 0.3
uM
4
IL-4
16.5 26
N2586 IL-6 100
ug/mL
4
IL-4
25.5 36
N2586 EO1428 1.0
uM
IL-6 100
ug/mL
4
IL-4
28.0 45