Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)
- Detail
- Small Molecules Studied
- Primary Cells Studied
- Proteins Studied
- Unclassified Perturbagens Studied
- Data Columns
- Results
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Protein Stimulus | Other Stimulus | Stimulus Concentration | Stimulus Conc Unit | ExpPlate | Measured Protein | Measured Protein MFI (a.u.) | Bead Count |
|---|---|---|---|---|---|---|---|---|---|---|---|
| N2586 | PD184352 | 0.1 | uM | Visfatin | 1 | ng/mL | 1 | IL-6 | 4529.0 | 58 | |
| N2586 | Lestaurtinib | 0.3 | uM | Visfatin | 1 | ng/mL | 1 | IL-6 | 4001.5 | 68 | |
| N2586 | Ruxolitinib | 0.3 | uM | Visfatin | 1 | ng/mL | 1 | IL-6 | 3144.5 | 68 | |
| N2586 | Tofacitinib | 0.3 | uM | Visfatin | 1 | ng/mL | 1 | IL-6 | 3520.0 | 65 | |
| N2586 | IKK16 | 2.0 | uM | Visfatin | 1 | ng/mL | 1 | IL-6 | 4636.5 | 34 | |
| 0 | IL-6 | 21.0 | 61 | ||||||||
| RA2159 | Poly(I:C) | 2 | ug/mL | 1 | IL-6 | 16926.0 | 61 | ||||
| RA2159 | PD184352 | 0.1 | uM | Poly(I:C) | 2 | ug/mL | 1 | IL-6 | 12197.0 | 63 | |
| RA2159 | Lestaurtinib | 0.3 | uM | Poly(I:C) | 2 | ug/mL | 1 | IL-6 | 5586.0 | 51 | |
| RA2159 | Ruxolitinib | 0.3 | uM | Poly(I:C) | 2 | ug/mL | 1 | IL-6 | 11660.0 | 37 | |
| RA2159 | Tofacitinib | 0.3 | uM | Poly(I:C) | 2 | ug/mL | 1 | IL-6 | 13768.0 | 67 | |
| RA2159 | IKK16 | 2.0 | uM | Poly(I:C) | 2 | ug/mL | 1 | IL-6 | 9211.5 | 66 | |
| N2586 | Poly(I:C) | 2 | ug/mL | 1 | IL-6 | 20600.0 | 50 | ||||
| N2586 | PD184352 | 0.1 | uM | Poly(I:C) | 2 | ug/mL | 1 | IL-6 | 16994.0 | 63 | |
| N2586 | Lestaurtinib | 0.3 | uM | Poly(I:C) | 2 | ug/mL | 1 | IL-6 | 3452.0 | 71 | |
| N2586 | Ruxolitinib | 0.3 | uM | Poly(I:C) | 2 | ug/mL | 1 | IL-6 | 10394.0 | 56 | |
| N2586 | Tofacitinib | 0.3 | uM | Poly(I:C) | 2 | ug/mL | 1 | IL-6 | 14549.5 | 50 | |
| N2586 | IKK16 | 2.0 | uM | Poly(I:C) | 2 | ug/mL | 1 | IL-6 | 12428.0 | 56 | |
| 0 | IL-6 | 21.0 | 50 | ||||||||
| RA2159 | 2 | IL-6 | 3542.5 | 72 | |||||||
| RA2159 | EO1428 | 1.0 | uM | 2 | IL-6 | 2904.0 | 76 | ||||
| RA2159 | PI103 | 0.1 | uM | 2 | IL-6 | 6552.0 | 70 | ||||
| RA2159 | Sigma A6730 | 3.0 | uM | 2 | IL-6 | 5819.0 | 62 | ||||
| RA2159 | JNK-IN-8 | 3.0 | uM | 2 | IL-6 | 4584.0 | 49 | ||||
| RA2159 | JNK-IN-11 | 0.3 | uM | 2 | IL-6 | 5670.0 | 81 |