Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2586 Leptin 1
ng/mL
 3
IL-1B
 15.0 55
N2586 PD184352 0.1
uM
 Leptin 1
ng/mL
 3
IL-1B
 16.0 61
N2586 Lestaurtinib 0.3
uM
 Leptin 1
ng/mL
 3
IL-1B
 13.0 55
N2586 Ruxolitinib 0.3
uM
 Leptin 1
ng/mL
 3
IL-1B
 13.0 71
N2586 Tofacitinib 0.3
uM
 Leptin 1
ng/mL
 3
IL-1B
 13.0 63
N2586 IKK16 2.0
uM
 Leptin 1
ng/mL
 3
IL-1B
 15.5 54
RA2159 Adiponectin 5
ng/mL
 3
IL-1B
 16.0 56
RA2159 PD184352 0.1
uM
 Adiponectin 5
ng/mL
 3
IL-1B
 14.5 82
RA2159 Lestaurtinib 0.3
uM
 Adiponectin 5
ng/mL
 3
IL-1B
 14.0 79
RA2159 Ruxolitinib 0.3
uM
 Adiponectin 5
ng/mL
 3
IL-1B
 14.0 51
RA2159 Tofacitinib 0.3
uM
 Adiponectin 5
ng/mL
 3
IL-1B
 15.0 73
RA2159 IKK16 2.0
uM
 Adiponectin 5
ng/mL
 3
IL-1B
 14.0 71
N2586 Adiponectin 5
ng/mL
 3
IL-1B
 16.5 50
N2586 PD184352 0.1
uM
 Adiponectin 5
ng/mL
 3
IL-1B
 12.0 71
N2586 Lestaurtinib 0.3
uM
 Adiponectin 5
ng/mL
 3
IL-1B
 16.0 67
N2586 Ruxolitinib 0.3
uM
 Adiponectin 5
ng/mL
 3
IL-1B
 15.0 61
N2586 Tofacitinib 0.3
uM
 Adiponectin 5
ng/mL
 3
IL-1B
 15.0 65
N2586 IKK16 2.0
uM
 Adiponectin 5
ng/mL
 3
IL-1B
 15.5 56
RA2159 IGF-I 100
ug/mL
 3
IL-1B
 12.0 54
RA2159 PD184352 0.1
uM
 IGF-I 100
ug/mL
 3
IL-1B
 12.0 55
RA2159 Lestaurtinib 0.3
uM
 IGF-I 100
ug/mL
 3
IL-1B
 12.5 66
RA2159 Ruxolitinib 0.3
uM
 IGF-I 100
ug/mL
 3
IL-1B
 12.0 59
RA2159 Tofacitinib 0.3
uM
 IGF-I 100
ug/mL
 3
IL-1B
 15.0 55
RA2159 IKK16 2.0
uM
 IGF-I 100
ug/mL
 3
IL-1B
 15.5 56
RA2159 3
IL-1B
 14.0 72