Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2159 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
M-CSF
 310.0 63
RA2159 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
M-CSF
 129.0 53
RA2159 PI103 0.1
uM
 1
M-CSF
 156.0 62
N2586 IL-1 alpha 100
ng/mL
 1
M-CSF
 437.0 52
N2586 PD184352 0.1
uM
 IL-1 alpha 100
ng/mL
 1
M-CSF
 373.0 51
N2586 Lestaurtinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
M-CSF
 495.0 59
N2586 Ruxolitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
M-CSF
 513.5 68
N2586 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
M-CSF
 524.5 78
N2586 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
M-CSF
 236.0 50
N2586 PI103 0.1
uM
 1
M-CSF
 159.0 44
RA2159 IL-6 100
ug/mL
 1
M-CSF
 140.0 55
RA2159 PD184352 0.1
uM
 IL-6 100
ug/mL
 1
M-CSF
 142.0 60
RA2159 Lestaurtinib 0.3
uM
 IL-6 100
ug/mL
 1
M-CSF
 112.0 55
RA2159 Ruxolitinib 0.3
uM
 IL-6 100
ug/mL
 1
M-CSF
 137.5 68
RA2159 Tofacitinib 0.3
uM
 IL-6 100
ug/mL
 1
M-CSF
 134.0 67
RA2159 IKK16 2.0
uM
 IL-6 100
ug/mL
 1
M-CSF
 136.0 68
RA2159 Sigma A6730 3.0
uM
 1
M-CSF
 137.0 94
N2586 IL-6 100
ug/mL
 1
M-CSF
 202.5 70
N2586 PD184352 0.1
uM
 IL-6 100
ug/mL
 1
M-CSF
 204.0 72
N2586 Lestaurtinib 0.3
uM
 IL-6 100
ug/mL
 1
M-CSF
 158.0 61
N2586 Ruxolitinib 0.3
uM
 IL-6 100
ug/mL
 1
M-CSF
 162.5 44
N2586 Tofacitinib 0.3
uM
 IL-6 100
ug/mL
 1
M-CSF
 179.5 58
N2586 IKK16 2.0
uM
 IL-6 100
ug/mL
 1
M-CSF
 159.5 54
N2586 Sigma A6730 3.0
uM
 1
M-CSF
 169.0 63
RA2159 IL-17A 100
ng/mL
 1
M-CSF
 131.0 84