Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2586 Lestaurtinib 0.3
uM
 1
M-CSF
 165.5 82
N2586 Ruxolitinib 0.3
uM
 1
M-CSF
 189.0 70
N2586 Tofacitinib 0.3
uM
 1
M-CSF
 190.0 36
N2586 IKK16 2.0
uM
 1
M-CSF
 161.0 45
N2586 1
M-CSF
 173.0 43
0
M-CSF
 106.0 55
0
M-CSF
 60.0 41
RA2159 TNF-a 100
ng/mL
 1
M-CSF
 288.0 51
RA2159 PD184352 0.1
uM
 TNF-a 100
ng/mL
 1
M-CSF
 258.5 70
RA2159 Lestaurtinib 0.3
uM
 TNF-a 100
ng/mL
 1
M-CSF
 323.5 64
RA2159 Ruxolitinib 0.3
uM
 TNF-a 100
ng/mL
 1
M-CSF
 320.5 68
RA2159 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
M-CSF
 357.0 68
RA2159 IKK16 2.0
uM
 TNF-a 100
ng/mL
 1
M-CSF
 189.5 74
RA2159 EO1428 1.0
uM
 1
M-CSF
 171.0 68
N2586 TNF-a 100
ng/mL
 1
M-CSF
 455.0 51
N2586 PD184352 0.1
uM
 TNF-a 100
ng/mL
 1
M-CSF
 463.5 34
N2586 Lestaurtinib 0.3
uM
 TNF-a 100
ng/mL
 1
M-CSF
 416.5 36
N2586 Ruxolitinib 0.3
uM
 TNF-a 100
ng/mL
 1
M-CSF
 497.5 70
N2586 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
M-CSF
 451.0 67
N2586 IKK16 2.0
uM
 TNF-a 100
ng/mL
 1
M-CSF
 319.0 48
N2586 EO1428 1.0
uM
 1
M-CSF
 168.0 67
RA2159 IL-1 alpha 100
ng/mL
 1
M-CSF
 344.5 54
RA2159 PD184352 0.1
uM
 IL-1 alpha 100
ng/mL
 1
M-CSF
 266.0 69
RA2159 Lestaurtinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
M-CSF
 317.0 63
RA2159 Ruxolitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
M-CSF
 374.0 61