Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2586 PD184352 0.1
uM
 IL-6 100
ug/mL
 3
TRAIL
 42.0 58
N2586 Lestaurtinib 0.3
uM
 IL-6 100
ug/mL
 3
TRAIL
 37.0 63
N2586 Ruxolitinib 0.3
uM
 IL-6 100
ug/mL
 3
TRAIL
 42.0 74
N2586 Tofacitinib 0.3
uM
 IL-6 100
ug/mL
 3
TRAIL
 33.5 52
N2586 IKK16 2.0
uM
 IL-6 100
ug/mL
 3
TRAIL
 37.5 82
N2586 Sigma A6730 3.0
uM
 3
TRAIL
 46.0 65
RA2159 IL-1 alpha 100
ng/mL
 3
TRAIL
 45.0 68
RA2159 PD184352 0.1
uM
 IL-1 alpha 100
ng/mL
 3
TRAIL
 45.0 65
RA2159 Lestaurtinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
TRAIL
 51.5 76
RA2159 Ruxolitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
TRAIL
 50.0 53
RA2159 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
TRAIL
 41.0 71
RA2159 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
TRAIL
 34.0 61
RA2159 PI103 0.1
uM
 3
TRAIL
 26.5 62
N2586 IL-1 alpha 100
ng/mL
 3
TRAIL
 105.0 72
N2586 PD184352 0.1
uM
 IL-1 alpha 100
ng/mL
 3
TRAIL
 147.0 67
N2586 Lestaurtinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
TRAIL
 116.0 67
N2586 Ruxolitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
TRAIL
 143.0 65
N2586 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
TRAIL
 50.0 60
N2586 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
TRAIL
 53.0 63
N2586 PI103 0.1
uM
 3
TRAIL
 39.0 61
0
TRAIL
 21.5 54
RA2159 TNF-a 100
ng/mL
 3
TRAIL
 72.0 53
RA2159 PD184352 0.1
uM
 TNF-a 100
ng/mL
 3
TRAIL
 66.0 76
RA2159 Lestaurtinib 0.3
uM
 TNF-a 100
ng/mL
 3
TRAIL
 63.0 87
RA2159 Ruxolitinib 0.3
uM
 TNF-a 100
ng/mL
 3
TRAIL
 60.0 51