Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2159 Ruxolitinib 0.3
uM
 2
TRAIL
 26.5 52
N2586 IL-6 100
ug/mL
 2
TRAIL
 38.0 60
N2586 EO1428 1.0
uM
 IL-6 100
ug/mL
 2
TRAIL
 43.0 86
N2586 PI103 0.1
uM
 IL-6 100
ug/mL
 2
TRAIL
 38.0 65
N2586 Sigma A6730 3.0
uM
 IL-6 100
ug/mL
 2
TRAIL
 40.0 59
N2586 JNK-IN-8 3.0
uM
 IL-6 100
ug/mL
 2
TRAIL
 33.5 60
N2586 JNK-IN-11 0.3
uM
 IL-6 100
ug/mL
 2
TRAIL
 35.0 57
N2586 Ruxolitinib 0.3
uM
 2
TRAIL
 40.0 51
RA2159 IL-17A 100
ng/mL
 2
TRAIL
 28.0 81
RA2159 EO1428 1.0
uM
 IL-17A 100
ng/mL
 2
TRAIL
 32.5 68
RA2159 PI103 0.1
uM
 IL-17A 100
ng/mL
 2
TRAIL
 29.0 66
RA2159 Sigma A6730 3.0
uM
 IL-17A 100
ng/mL
 2
TRAIL
 30.0 72
RA2159 JNK-IN-8 3.0
uM
 IL-17A 100
ng/mL
 2
TRAIL
 23.0 55
RA2159 JNK-IN-11 0.3
uM
 IL-17A 100
ng/mL
 2
TRAIL
 25.0 40
RA2159 Tofacitinib 0.3
uM
 2
TRAIL
 27.0 33
N2586 IL-17A 100
ng/mL
 2
TRAIL
 46.5 48
N2586 EO1428 1.0
uM
 IL-17A 100
ng/mL
 2
TRAIL
 55.0 48
N2586 PI103 0.1
uM
 IL-17A 100
ng/mL
 2
TRAIL
 37.0 11
N2586 Sigma A6730 3.0
uM
 IL-17A 100
ng/mL
 2
TRAIL
 52.0 20
N2586 JNK-IN-8 3.0
uM
 IL-17A 100
ng/mL
 2
TRAIL
 36.0 50
N2586 JNK-IN-11 0.3
uM
 IL-17A 100
ng/mL
 2
TRAIL
 41.0 67
N2586 Tofacitinib 0.3
uM
 2
TRAIL
 40.5 82
RA2159 2
TRAIL
 29.0 92
RA2159 EO1428 1.0
uM
 2
TRAIL
 28.5 84
RA2159 PI103 0.1
uM
 2
TRAIL
 24.0 66