Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2159 Sigma A6730 3.0
uM
 4
SCF
 44.5 60
RA2159 JNK-IN-8 3.0
uM
 4
SCF
 43.0 41
RA2159 JNK-IN-11 0.3
uM
 4
SCF
 36.0 19
RA2159 IKK16 2.0
uM
 4
SCF
 47.5 10
N2586 4
SCF
 67.0 10
N2586 EO1428 1.0
uM
 4
SCF
 93.5 10
N2586 PI103 0.1
uM
 4
SCF
 55.0 65
N2586 Sigma A6730 3.0
uM
 4
SCF
 71.0 56
N2586 JNK-IN-8 3.0
uM
 4
SCF
 60.5 52
N2586 JNK-IN-11 0.3
uM
 4
SCF
 46.0 47
N2586 IKK16 2.0
uM
 4
SCF
 62.5 62
RA2159 IL-17A 100
ng/mL
 4
SCF
 37.0 65
RA2159 EO1428 1.0
uM
 IL-17A 100
ng/mL
 4
SCF
 40.5 84
RA2159 PI103 0.1
uM
 IL-17A 100
ng/mL
 4
SCF
 38.5 64
RA2159 Sigma A6730 3.0
uM
 IL-17A 100
ng/mL
 4
SCF
 40.0 67
RA2159 JNK-IN-8 3.0
uM
 IL-17A 100
ng/mL
 4
SCF
 42.0 80
RA2159 JNK-IN-11 0.3
uM
 IL-17A 100
ng/mL
 4
SCF
 38.0 63
RA2159 Tofacitinib 0.3
uM
 4
SCF
 33.0 32
N2586 IL-17A 100
ng/mL
 4
SCF
 72.0 62
N2586 EO1428 1.0
uM
 IL-17A 100
ng/mL
 4
SCF
 82.5 56
N2586 PI103 0.1
uM
 IL-17A 100
ng/mL
 4
SCF
 84.0 54
N2586 Sigma A6730 3.0
uM
 IL-17A 100
ng/mL
 4
SCF
 65.0 49
N2586 JNK-IN-8 3.0
uM
 IL-17A 100
ng/mL
 4
SCF
 63.0 66
N2586 JNK-IN-11 0.3
uM
 IL-17A 100
ng/mL
 4
SCF
 46.0 76
N2586 Tofacitinib 0.3
uM
 4
SCF
 44.0 60