Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2586 Tofacitinib 0.3
uM
 IL-17A 100
ng/mL
 1
SCF
 44.5 30
N2586 IKK16 2.0
uM
 IL-17A 100
ng/mL
 1
SCF
 67.0 53
RA2159 1
SCF
 42.0 55
RA2159 PD184352 0.1
uM
 1
SCF
 53.0 78
RA2159 Lestaurtinib 0.3
uM
 1
SCF
 38.5 82
RA2159 Ruxolitinib 0.3
uM
 1
SCF
 40.0 73
RA2159 Tofacitinib 0.3
uM
 1
SCF
 37.0 68
RA2159 IKK16 2.0
uM
 1
SCF
 37.0 71
RA2159 JNK-IN-8 3.0
uM
 1
SCF
 38.0 51
N2586 1
SCF
 65.0 63
N2586 PD184352 0.1
uM
 1
SCF
 64.0 52
N2586 Lestaurtinib 0.3
uM
 1
SCF
 59.5 68
N2586 Ruxolitinib 0.3
uM
 1
SCF
 63.0 70
N2586 Tofacitinib 0.3
uM
 1
SCF
 56.0 62
N2586 IKK16 2.0
uM
 1
SCF
 56.0 50
N2586 JNK-IN-8 3.0
uM
 1
SCF
 60.0 29
RA2159 EGF 100
ng/mL
 1
SCF
 49.0 53
RA2159 PD184352 0.1
uM
 EGF 100
ng/mL
 1
SCF
 40.0 69
RA2159 Lestaurtinib 0.3
uM
 EGF 100
ng/mL
 1
SCF
 38.0 60
RA2159 Ruxolitinib 0.3
uM
 EGF 100
ng/mL
 1
SCF
 43.0 62
RA2159 Tofacitinib 0.3
uM
 EGF 100
ng/mL
 1
SCF
 44.5 74
RA2159 IKK16 2.0
uM
 EGF 100
ng/mL
 1
SCF
 39.0 85
RA2159 JNK-IN-11 0.3
uM
 1
SCF
 38.0 93
N2586 EGF 100
ng/mL
 1
SCF
 73.0 73
N2586 PD184352 0.1
uM
 EGF 100
ng/mL
 1
SCF
 72.0 81